Recombinant Mouse PAD2, GST-tagged

• Cat.No.: PADI2-6979M
• Product Overview: Recombinant full-length mouse PAD2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: PAD2 is a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. PAD2 has peptidylarginine deiminase activity against synthetic substrates. PAD2 is mainly expressed in the central nervous system, skeletal muscle, spinal cord, cerebrum, cerebellum, and submaxillary gland. PAD2 play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis.
• Source: Sf9 Cells
• Species: Mouse
• Tag: GST
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~99 kDa
• Protein length: Full length
• Purity: >95%
• Applications: Western Blot
• Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
• Concentration: 0.1 μg/μ

Gene Information

• Gene Name: Padi2 peptidyl arginine deiminase, type II [ Mus musculus ]
• Official Symbol: PADI2
• Synonyms: PADI2; peptidyl arginine deiminase, type II; protein-arginine deiminase type-2; PAD type II; peptidylarginine deiminase II; protein-arginine deiminase type II; Pdi; Pdi2; mKIAA0994
• Gene ID: 18600
• mRNA Refseq: NM_008812
• Protein Refseq: NP_032838
• Pathway: protein citrullination, organism-specific biosystem
• Function: calcium ion binding; hydrolase activity; protein-arginine deiminase activity