Recombinant Mouse AATK, GST-tagged

• Cat.No.: AATK-6993M
• Product Overview: Recombinant mouse AATK (8-411) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: AATK or apoptosis-associated tyrosine kinase contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. AATK is induced during apoptosis, and expression of this protein is a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. AATK is highly detected in brain, lung, kidney, and pancreas. AATK is also shown to produce neuronal differentiation in a neuroblastoma cell line.
• Source: Sf9 Cells
• Species: Mouse
• Tag: GST
• Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Molecular Mass: ~71 kDa
• Protein length: 8-411 aa
• Purity: >95%
• Applications: Western Blot
• Storage: Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles.
• Concentration: 0.1 μg/μl

Gene Information

• Gene Name: Aatk apoptosis-associated tyrosine kinase [ Mus musculus ]
• Official Symbol: AATK
• Synonyms: AATK; apoptosis-associated tyrosine kinase; serine/threonine-protein kinase LMTK1; lemur tyrosine kinase 1; apoptosis-associated tyrosine kinase 1B; brain apoptosis-associated tyrosine kinase; AATYK; aatyk1; mKIAA0641
• Gene ID: 11302
• mRNA Refseq: NM_001198785
• Protein Refseq: NP_001185714
• Function: ATP binding; kinase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; protein tyrosine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups