Recombinant Human CDKL5 Protein, His-tagged

• Cat.No.: CDKL5-7022H
• Product Overview: Recombinant human CDKL5 (1-498) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: This gene is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized.
• Source: Insect cell
• Species: Human
• Tag: GST
• Molecular Mass: 84 kDa
• Protein length: 1-498
• Purity: >85%
• Stability: One year at -70 centigrade from date of shipment.
• Storage: Store product at–70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 μg/μL
• Storage Buffer: 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT,0.1mM PMSF,25% glycerol.
• Shipping: Dry ice

Gene Information

• Gene Name: CDKL5 cyclin dependent kinase like 5 [ Homo sapiens (human) ]
• Official Symbol: CDKL5
• Synonyms: CDKL5; cyclin dependent kinase like 5; DEE2; ISSX; STK9; EIEE2; CFAP247; cyclin-dependent kinase-like 5; cyclin dependent kinase 5 transcript; serine/threonine kinase 9; serine/threonine-protein kinase 9; EC 2.7.11.22
• Gene ID: 6792
• mRNA Refseq: NM_003159
• Protein Refseq: NP_003150
• MIM: 300203
• UniProt ID: O76039