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Goat Anti-Human Hemoglobin PAb, HRP-Conjugation

Cat.No. : CPBTT-30937GH
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  • Gene Information
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Cat. No. : CPBTT-30937GH
ProductOverview : Goat polyclonal to human hemoglobin (HRP).
Antigen Description : The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
Immunogen : Goats were immunized with purified human hemoglobin. After multiple immunizations in Freunds adjuvant the goats were bled and serum collected. The antibodies were isolated by immunoaffinity chromatography and conjugated with horseradish peroxidase
Host animal : Goat
Species : Human
Conjugation : HRP
Target : Hemoglobin
Form : Liquid
Storage Buffer : 50 mM HEPES, 0.1 M Sodium Chloride with 0.2% BSA, 0.01% Thimerosal
Concentration : 1 mg/ml
Storage : Keep as concentrated solution, aliquot and store at 4°C.
Note : For Research and Manufacturing Only; Not for Use in Diagnostic Applications. The affinity purified antibody forms a single line of precipitation with human adult hemoglobin A1, A2, F and S by immunoelectrophoresis. There is no reaction with human serum proteins. Suggested starting dilutions are 1:10,0001:50,000 but optimal working dilutions should be determined for your particular assay conditions."
Gene Name : HBA1 hemoglobin, alpha 1 [ Homo sapiens ]
Official Symbol : HBA1
Synonyms : HBA1; hemoglobin, alpha 1; HBH; CD31; hemoglobin subunit alpha; alpha-globin; alpha-1 globin; alpha-1-globin; alpha one globin; hemoglobin alpha chain; hemoglobin alpha-1 chain; hemoglobin alpha 1 globin chain; MGC126895; MGC126897; Hemoglobin alpha 2; 142200; 3047; 3043; Hemoglobin; 3039; HSGGL1; HBB; HBG1; HBGR; CD113t-C; 141800; CD113tC; P68871; 141900; Q3MIF5; HBGA; PRO2979; P69891; CD113t C
Gene ID : 3039
mRNA Refseq : NM_000558
Protein Refseq : NP_000549
MIM : 141800
UniProt ID : P69905
Chromosome Location : 16p13.3
Pathway : African trypanosomiasis; Malaria; Metabolism; O2/CO2 exchange in erythrocytes; Selenium Pathway; Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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