"BCL7A" Related Products

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Recombinant Human BCL7A, His-tagged

Cat.No.: BCL7A-7072H
Product Overview: Recombinant human BCL7A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: BCL7A is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl,10% glycerol, 1mM DTT, 2mM EDTA
Molecular Mass: 25.2 kDa (233aa)
Protein length: 1-210aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSGRSVR AETRSRAKDD IKRVMAAIEK VRKWEKKWVT VGDTSLRIYK WVPVTEPKVD DKNKNKKKGKDEKCGSEVTT PENSSSPGMM DMHDDNSNQS SIADASPIKQ ENSSNSSPAP EPNSAVPSDG TEAKVDEAQA DGKEHPGAED ASDEQNSQSS MEHSMNSSEK VDRQPSGDSG LAAETSAISQ DLEGVPPSKK MKLEASQQNS EEM
Purity: >85% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 0.25 mg/ml
Gene Name: BCL7A B-cell CLL/lymphoma 7A [ Homo sapiens ]
Official Symbol: BCL7A
Synonyms: BCL7A; B-cell CLL/lymphoma 7A; BCL7; B-cell CLL/lymphoma 7 protein family member A; B-cell CLL/lymphoma-7;
Gene ID: 605
mRNA Refseq: NM_001024808
Protein Refseq: NP_001019979
MIM: 601406
UniProt ID: Q4VC05
Chromosome Location: 12q24.1
Function: molecular_function;

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