Recombinant Human AICDA, His-tagged
Cat.No. : | AICDA-7113H |
Product Overview : | Recombinant human AICDA protein, fused to His-tag at N-terminus, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | AICDA, also known as AID, is involved in somatic hypermutation, gene conversion, and class-switch recombination in B-lymphocytes. This protein is required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses. It may also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol |
Molecular Mass : | 26.1kDa (218aa) |
Protein length : | 1-198aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MDSLLMNRRK FLYQFKNVRW AKGRRETYLC YVVKRRDSAT SFSLDFGYLR NKNGCHVELL FLRYISDWDL DPGRCYRVTW FTSWSPCYDC ARHVADFLRG NPNLSLRIFT ARLYFCEDRK AEPEGLRRLH RAGVQIAIMT FKDYFYCWNT FVENHERTFK AWEGLHENSV RLSRQLRRIL LPLYEVDDLR DAFRTLGL |
Purity : | >85% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml |
Gene Name : | AICDA activation-induced cytidine deaminase [ Homo sapiens ] |
Official Symbol : | AICDA |
Synonyms : | AICDA; activation-induced cytidine deaminase; AID; ARP2; CDA2; HIGM2; cytidine aminohydrolase; integrated into Burkitts lymphoma cell line Ramos; |
Gene ID : | 57379 |
mRNA Refseq : | NM_020661 |
Protein Refseq : | NP_065712 |
MIM : | 605257 |
UniProt ID : | Q9GZX7 |
Chromosome Location : | 12p13 |
Pathway : | IL4-mediated signaling events, organism-specific biosystem; Intestinal immune network for IgA production, organism-specific biosystem; Intestinal immune network for IgA production, conserved biosystem; Primary immunodeficiency, organism-specific biosystem; Primary immunodeficiency, conserved biosystem; salvage pathways of pyrimidine deoxyribonucleotides, organism-specific biosystem; salvage pathways of pyrimidine ribonucleotides, organism-specific biosystem; |
Function : | cytidine deaminase activity; cytidine deaminase activity; hydrolase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines; metal ion binding; protein binding; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
AICDA-409M | Recombinant Mouse AICDA Protein, His (Fc)-Avi-tagged | +Inquiry |
AICDA-2783H | Recombinant Human AICDA Protein (1-198 aa), His-Myc-tagged | +Inquiry |
AICDA-0089H | Recombinant Human AICDA Protein (Gly23-Leu183), N-His-tagged | +Inquiry |
AICDA-1447M | Recombinant Mouse AICDA Protein | +Inquiry |
AICDA-1565H | Recombinant Human AICDA protein | +Inquiry |
◆ Lysates | ||
AICDA-8958HCL | Recombinant Human AICDA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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