"ezrin" Related Products

Recombinant Human Ezrin, His-tagged

Cat. No.: EZR-516H
Product Overview: Recombinant Human Ezrin,encoding the mature form of human EZR(Pro2-Leu586) was expressed with a his tag at the N-terminus.
Description: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.
Source: E. coli
Molecular Mass: The recombinant human EZR consists of 601 amino acids and predicts a molecular mass of 71.2 KDa. It migrates as an approximately 82 KDa band in SDS-PAGE under reducing conditions.
Predicted N terminal: His
Formulation: Lyophilized from a 0.2μm filtered solution of PBS 100mM Arg 10% glycerol, 0.1%Twen 20, pH 7.5.
Purity: Greater than 60% as determined by SDS-PAGE
Stability: Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name: EZR ezrin [ Homo sapiens ]
Official Symbol: EZR
Synonyms: EZR; ezrin; VIL2, villin 2 (ezrin); cytovillin 2 CVL; CVIL; ezrin; p81; villin-2; cytovillin 2
Gene ID: 7430
mRNA Refseq: NM_001111077
Protein Refseq: NP_001104547
MIM: 123900
UniProt ID: P15311
Chromosome Location: 6q25.3
Pathway: Axon guidance; Developmental Biology; Gastric acid secretion
Function: actin filament binding; cell adhesion molecule binding ; protein binding

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