"LITAF" Related Products

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Recombinant Human LITAF, His-tagged

Cat.No.: LITAF-7246H
product overview: Recombinant human LITAF protein, fused to His-tag at N-terminus, was expressed in E.coli.
description: Lipopolysaccharide-induced TNF-alpha factor, also known as LITAF, is a small integral membrane protein of lysosome/late endosome. LITAF mediates the expression of inflammatory cytokines such as TNF-alpha in Lipopolysaccharide-induced processes. LITAF binds to STAT6B, a member of the STAT6 family forming a complex on the TNF-alpha promoter that modulates TNF activity. High levels of expression of LITAF mRNA have been observed predominantly in the placenta, peripheral blood leukocytes, lymph nodes and spleen.
source: E. coli
species: Human
tag: His
form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
molecular mass: 19.2 kDa (181aa)
protein length: 1-161aa
aa sequence: MGSSHHHHHH SSGLVPRGSH MSVPGPYQAA TGPSSAPSAP PSYEETVAVN SYYPTPPAPM PGPTTGLVTG PDGKGMNPPS YYTQPAPIPNNNPITVQTVY VQHPITFLDR PIQMCCPSCN KMIVSQLSYN AGALTWLSCG SLCLLGCIAG CCFIPFCVDA LQDVDHYCPN CRALLGTYKR L
purity: >85% by SDS - PAGE
applications: SDS-PAGE
storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
concentration: 1 mg/ml
gene name: LITAF lipopolysaccharide-induced TNF factor [ Homo sapiens ]
official symbol: LITAF
synonyms: LITAF; lipopolysaccharide-induced TNF factor; lipopolysaccharide-induced tumor necrosis factor-alpha factor; FLJ38636; PIG7; SIMPLE; TP53I7; p53-induced gene 7 protein; LPS-induced TNF-alpha factor; tumor protein p53 inducible protein 7; lipopolysaccharide-induced TNF-alpha factor; small integral membrane protein of lysosome/late endosome; MGC116698; MGC116700; MGC116701; MGC125274; MGC125275; MGC125276;
Gene ID: 9516
mrna refseq: NM_001136472
protein refseq: NP_001129944
mim: 603795
uniprot id: Q99732
chromosome location: 16p13.3-p12
function: WW domain binding; signal transducer activity;

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