Recombinant Human POLR2J2, His-tagged
Cat.No. : | POLR2J2-7252H |
- Specification
- Gene Information
- Related Products
product overview : | Recombinant human POLR2J2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
description : | POLR2J2 is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3" end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo. |
source : | E. coli |
species : | Human |
tag : | His |
form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT, 250mM Imidazole |
molecular mass : | 15.5 kDa (138aa) |
protein length : | 1-115aa |
aa sequence : | MGSSHHHHHH SSGLVPRGSH MGSMNAPPAF ESFLLFEGEK ITINKDTKVP KACLFTINKE DHTLGNIIKS QLLKDPQVLF AGYKVPHPLEHKIIIRVQTT PDYSPQEAFT NAITDLISEL SLLEERFRTC LLPLRLLP |
purity : | >95% by SDS - PAGE |
applications : | SDS-PAGE |
storage : | Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
concentration : | 0.25 mg/ml |
gene name : | POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2 [ Homo sapiens ] |
official symbol : | POLR2J2 |
synonyms : | POLR2J2; polymerase (RNA) II (DNA directed) polypeptide J2; DNA-directed RNA polymerase II subunit RPB11-b1; RPB11b1; RNA polymerase II subunit B11-b1; DNA-directed RNA polymerase II subunit J2; DNA directed RNA polymerase II polypeptide J-related; HRPB11B; MGC54043; MGC105050; |
Gene ID : | 246721 |
mrna refseq : | NM_032959 |
protein refseq : | NP_116581 |
mim : | 609881 |
uniprot id : | Q9GZM3 |
chromosome location : | 7q22.1 |
pathway : | Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Metabolic pathways, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; Pyrimidine metabolism, organism-specific biosystem; Pyrimidine metabolism, conserved biosystem; |
function : | DNA binding; DNA-directed RNA polymerase activity; |
Products Types
◆ Recombinant Protein | ||
POLR2J2-321H | Recombinant Human POLR2J2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
POLR2J2-3029HCL | Recombinant Human POLR2J2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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