Recombinant Human RAB10, His-tagged

• Cat.No.: RAB10-7263H

Specification

• product overview: Recombinant human RAB10 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• description: RAB10 is a member of the Ras superfamily of small GTP-binding proteins. This protein is a key regulator of endocytic recycling, especially in the basolateral recycling pathways of polarized epithelial cells. It is required for the recruitment of CNT-1 to endosomal membranes in the intestinal epithelium.
• source: E. coli
• species: Human
• tag: His
• form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
• molecular mass: 24.7 kDa(220aa)
• protein length: 1-200aa
• aa sequence: MGSSHHHHHH SSGLVPRGSH MAKKTYDLLF KLLLIGDSGV GKTCVLFRFS DDAFNTTFIS TIGIDFKIKT VELQGKKIKL QIWDTAGQERFHTITTSYYR GAMGIMLVYD ITNGKSFENI SKWLRNIDEH ANEDVERMLL GNKCDMDDKR VVPKGKGEQI AREHGIRFFE TSAKANINIEKAFLTLAEDI LRKTPVKEPN SENVDISSGG GVTGWKSKCC
• purity: >90% by SDS - PAGE
• applications: SDS-PAGE
• storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• concentration: 0.5 mg/ml

Gene Information

• gene name: RAB10 RAB10, member RAS oncogene family [ Homo sapiens ]
• official symbol: RAB10
• synonyms: RAB10; RAB10, member RAS oncogene family; ras-related protein Rab-10; ras related GTP binding protein; GTP-binding protein RAB10; ras-related GTP-binding protein
• Gene ID: 10890
• mrna refseq: NM_016131
• protein refseq: NP_057215
• mim: 612672
• uniprot id: P61026
• chromosome location: 2p23.3
• function: GTP binding; nucleotide binding