||Recombinant Human CD14 (aa 1-201) expressed in E.coli, shows a 50 kDa band on SDS-PAGE. The CD14 is purified by proprietary chromatographic techniques.
||CD14 (also known lipopolysaccharide (LPS) receptor) is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. CD14 has been shown to bind apoptotic cells.
||Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD14; CD14 antigen; CD14 molecule.
||Sterile Filtered clear solution.
||CD14 at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
||• ELISA • Inhibition Assays • Western Blotting
||Store vial at -20℃ to -80℃. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.