Recombinant Human RAB4A, His-tagged

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Recombinant Human RAB4A, His-tagged

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Cat. No. : RAB4A-3556H
Product Overview : Recombinant human RAB4A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography (1-218aa).
Description : RAB4A belongs to the small GTPase superfamily. RAB4A has been shown to interact with STX4, RAB11FIP1, RABEP1, CD2AP and KIF3B. Rab4 is also involved in the translocation of glucose transporter (Glu4) in adipocytes in response to insulin. Overexpression of Rab4 causes a redistribution of receptors on plasma membrane versus endocytic compartments.
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl,1mM DTT
Molecular Weight : 26.5 kDa (238aa), confirmed by MALDI-TOF
Purity : > 90% by SDS - PAGE
Concentration : 1.0 mg/ml (determined by Bradford assay)
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MSQTAMSETY DFLFKFLVIG NAGTGKSCLL HQFIEKKFKD DSNHTIGVEF GSKIINVGGK YVKLQIWDTA GQERFRSVTR SYYRGAAGAL LVYDITSRET YNALTNWLTD ARMLASQNIV IILCGNKKDL DADREVTFLE ASRFAQENEL MFLETSALTG ENVEEAFVQC ARKILNKIES GELDPERMGS GIQYGDAALR QLRSPRRAQA PNAQECGC.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
PDBrendering based on 1yu9. :

Gene Name : RAB4A RAB4A, member RAS oncogene family [ Homo sapiens ]
Official Symbol : RAB4A
Synonyms : RAB4A; RAB4A, member RAS oncogene family; Oncogene RAB4; RAB4, member RAS oncogene family; ras-related protein Rab-4A; HRES-1/RAB4; RAB4
Gene ID : 5867
mRNA Refseq : NM_004578
Protein Refseq : NP_004569
MIM : 179511
UniProt ID : P20338
Chromosome Location : 1q42-q43
Function : GDP binding; GTPase activity; ionotropic glutamate receptor binding; protein transporter activity; syntaxin binding

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