"MLXIPL" Related Products

Recombinant Human MLXIPL, GST-tagged

Cat. No. : MLXIPL-111H
Product Overview : Recombinant Human MLXIPL (603 aa. - 700 aa.) fused with GST-tag at N-terminal, was expressed in vitro wheat germ system.
Description : This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.
Source : Wheat germ
Molecular Mass : 36.52 kDa
Sequence : PPAPSGSERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENRRITHISAEQKRRFNIKLGFDTLHGLVSTLSAQPSLKVSKATTLQKTAEYI
Purification : Glutathione Sepharose 4 Fast Flow
Storage buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Applications : ELISA; WB
Storage : Store at -80 °C. Aliquot to avoid repeated freezing and thawing.
Note : Best use within three months from the date of receipt of this protein.
OfficialSymbol : MLXIPL
Gene Name : MLXIPL MLX interacting protein-like [ Homo sapiens ]
Synonyms : MLX interacting protein-like; MIO; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14; MLXIPL; williams-Beuren syndrome chromosomal region 14 protein; Mlx interactor; MLX-interacting protein-like; class D basic helix-loop-helix protein 14; Williams Beuren syndrome chromosome region 14; carbohydrate response element binding protein; carbohydrate-responsive element-binding protein; WS basic-helix-loop-helix leucine zipper protein; Williams-Beuren syndrome chromosome region 14 protein 1; Williams-Beuren syndrome chromosome region 14 protein 2
Gene ID : 51085
mRNA Refseq : NM_032951
Protein Refseq : NP_116569
MIM : 605678
UniProt ID : Q9NP71
Chromosome Location : 7q11.23
Pathway : Integration of energy metabolism
Function : transcription repressor activity; transcription factor binding; transcription factor activity; transcription activator activity; protein homodimerization activity; protein heterodimerization activity; DNA binding

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