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Recombinant Human MLXIPL, GST-tagged

Cat.No. : MLXIPL-111H
Product Overview : Recombinant Human MLXIPL (603 aa. - 700 aa.) fused with GST-tag at N-terminal, was expressed in vitro wheat germ system.
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  • Gene Information
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Cat. No. : MLXIPL-111H
Description : This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.
Source : Wheat germ
Molecular Mass : 36.52 kDa
Sequence : PPAPSGSERRLSGDLSSMPGPGTLS VRVSPPQPILSRGRPDSNKTENRRI THISAEQKRRFNIKLGFDTLHGLVS TLSAQPSLKVSKATTLQKTAEYI
Purification : Glutathione Sepharose 4 Fast Flow
Storage buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Applications : ELISA; WB
Storage : Store at -80 °C. Aliquot to avoid repeated freezing and thawing.
Note : Best use within three months from the date of receipt of this protein.
OfficialSymbol : MLXIPL
Gene Name : MLXIPL MLX interacting protein-like [ Homo sapiens ]
Synonyms : MLX interacting protein-like; MIO; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14; MLXIPL; williams-Beuren syndrome chromosomal region 14 protein; Mlx interactor; MLX-interacting protein-like; class D basic helix-loop-helix protein 14; Williams Beuren syndrome chromosome region 14; carbohydrate response element binding protein; carbohydrate-responsive element-binding protein; WS basic-helix-loop-helix leucine zipper protein; Williams-Beuren syndrome chromosome region 14 protein 1; Williams-Beuren syndrome chromosome region 14 protein 2
Gene ID : 51085
mRNA Refseq : NM_032951
Protein Refseq : NP_116569
MIM : 605678
UniProt ID : Q9NP71
Chromosome Location : 7q11.23
Pathway : Integration of energy metabolism
Function : transcription repressor activity; transcription factor binding; transcription factor activity; transcription activator activity; protein homodimerization activity; protein heterodimerization activity; DNA binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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