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Mouse Anti-LTA Monoclonal Antibody

Cat.No. : DMABT-H19263
Product Overview : Mouse Anti-LTA Monoclonal Antibody
  • Specification
  • Gene Information
  • Related Products
Antigen Description : Tumor necrosis factor-beta (TNF-beta), also known as lymphotoxin-alpha (LT-alpha) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. TNF-beta possesses a signal peptide sequence and is a secreted protein; however, TNF-beta is also present on the surface of activated T, B and LAK cells as a complex with LT-beta. Bioactive TNF-beta exists as a homotrimer.
Target : LTA
Immunogen : E.coli expressed, recombinant human TNF-beta
Host : Mouse
Isotype : IgG1, kappa
species : Human
Clone : 460-349-9
Conjugation : N/A
Applications : ELISA,ELISPOT,Neut
Preparation : The LEAF (Low Endotoxin, Azide-Free) antibody was Purified by affinity chromatography.
Usage recommendation : Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 1-4 μg/ml is recommended. To obtain a linear standard curve, serial dilutions of TNF-beta recombinant protein ranging from 1000 to 8 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.
Concentration : 1.0 mg/ml
Storage : The antibody solution should be stored undiluted at 4 °C. This LEAF solution contains no preservative; handle under aseptic conditions.
Size : 500 μg
Gene Name : LTA lymphotoxin alpha (TNF superfamily, member 1) [ Homo sapiens ]
Official Symbol : LTA
Synonyms : LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1; LT-alpha; TNF-beta; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1;
Gene ID : 4049
mRNA Refseq : NM_000595
Protein Refseq : NP_000586
MIM : 153440
UniProt ID : P01374
Chromosome Location : 6p21.3
Pathway : Apoptosis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem;
Function : cytokine activity; receptor binding; tumor necrosis factor receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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