Recombinant Human SNAI2, GST-tagged
Cat.No. : | SNAI2-175H |
Product Overview : | Recombinant Human SNAI2 (97 a.a. - 169 a.a.) fused with GST-tag at N-terminal, was expressed in vitro wheat germ expression system. |
- Specification
- Gene Information
- Related Products
Cat. No. : | SNAI2-175H |
Description : | This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. |
Source : | wheat germ |
Molecular Mass : | 33.77 kDa |
Sequence : | KDHSGSESPISDEEERLQSKLSDPH AIEAEKFQCNLCNKTYSTFSGLAKH KQLHCDAQSRKSFSCKYCDKEYV |
Purification : | Glutathione Sepharose 4 Fast Flow |
Storage buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer. |
Applications : | ELISA; WB |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Note : | Best use within three months from the date of receipt of this protein. |
OfficialSymbol : | SNAI2 |
Gene Name : | SNAI2 snail homolog 2 (Drosophila) [ Homo sapiens ] |
Synonyms : | SLUG; WS2D; SLUGH1; SNAIL2; zinc finger protein SNAI2; protein snail homolog 2; neural crest transcription factor SLUG; slug (chicken homolog), zinc finger protein; snail homolog 2 (Drosophila); Neural crest transcription factor Slug; Protein snail homolog 2; slug homolog, zinc finger protein (chicken); SLUGH |
Gene ID : | 6591 |
mRNA Refseq : | NM_003068 |
Protein Refseq : | NP_003059 |
MIM : | 602150 |
UniProt ID : | O43623 |
Chromosome Location : | 8q11 |
Pathway : | Adherens junction; Direct p53 effectors; Neural Crest Differentiation; Regulation of Wnt-mediated beta catenin signaling and target gene transcription; Signaling events mediated by Stem cell factor receptor (c-Kit) |
Function : | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; chromatin binding; sequence-specific DNA binding; zinc ion binding |
Products Types
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SNAI2-8512M | Recombinant Mouse SNAI2 Protein, His (Fc)-Avi-tagged | +Inquiry |
SNAI2-4355R | Recombinant Rhesus monkey SNAI2 Protein, His-tagged | +Inquiry |
SNAI2-1879Z | Recombinant Zebrafish SNAI2 | +Inquiry |
◆ Lysates | ||
SNAI2-1642HCL | Recombinant Human SNAI2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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