"SYT4" Related Products

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Recombinant Human SYT4, His-tagged

Cat.No.: SYT4-7538H
Product Overview: Recombinant human SYT4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Antigen Description: Synaptotagmin-4, also known as SYT4, belongs to the synaptotagmin family proteins. Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. SYT4 is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus. The proximity of the SYT4 gene to markers of several psychiatric disorders suggest an involvement of SYT4 in human diseasee.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT
Molecular Mass: 46.1 kDa (409aa) confirmed by MALDI-TOF
Protein length: 38-425aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MCQRKSSKSN KTPPYKFVHV LKGVDIYPEN LNSKKKFGAD DKNEVKNKPA VPKNSLHLDL EKRDLNGNFP KTNLKPGSPS DLENATPKLF LEGEKESVSP ESLKSSTSLT SEEKQEKLGT LFFSLEYNFE RKAFVVNIKE ARGLPAMDEQ SMTSDPYIKM TILPEKKHKV KTRVLRKTLD PAFDETFTFY GIPYTQIQEL ALHFTILSFD RFSRDDIIGE VLIPLSGIEL SEGKMLMNRE IIKRNVRKSS GRGELLISLC YQSTTNTLTV VVLKARHLPK SDVSGLSDPY VKVNLYHAKK RISKKKTHVK KCTPNAVFNE LFVFDIPCEG LEDISVEFLV LDSERGSRNE VIGQLVLGAA AEGTGGEHWK EICDYPRRQI AKWHVLCDG
Purity: >90% as determined by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
Concentration: 0.25 mg/ml
Gene Name: SYT4 synaptotagmin IV [ Homo sapiens ]
Official Symbol: SYT4
Synonyms: SYT4; synaptotagmin IV; synaptotagmin-4; HsT1192; KIAA1342; sytIV; synaptotagmin 4;
Gene ID: 6860
mRNA Refseq: NM_020783
Protein Refseq: NP_065834
MIM: 600103
UniProt ID: Q9H2B2
Chromosome Location: 18q12.3
Function: calcium ion binding; transporter activity;

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