Recombinant Human MOB1B, His-tagged

• Cat.No.: MOB1B-7582H
• Product Overview: Recombinant human MOB1B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Antigen Description: MOB1B is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT.
• Molecular Mass: 27 kDa (239aa) confirmed by MALDI-TOF
• Protein length: 1-216aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSFLFGS RSSKTFKPKK NIPEGSHQYE LLKHAEATLG SGNLRMAVML PEGEDLNEWV AVNTVDFFNQ INMLYGTITD FCTEESCPVM SAGPKYEYHW ADGTNIKKPI KCSAPKYIDY LMTWVQDQLD DETLFPSKIG VPFPKNFMSV AKTILKRLFR VYAHIYHQHF DPVIQLQEEA HLNTSFKHFI FFVQEFNLID RRELAPLQEL IEKLTSKDR
• Purity: >95% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: MOB1B MOB kinase activator 1B [ Homo sapiens ]
• Official Symbol: MOB1B
• Synonyms: MOB1B; MOB kinase activator 1B; MOB1 Mps One Binder homolog B (yeast) , MOB1, Mps One Binder kinase activator like 1A (yeast) , MOBKL1A; MOB4A; Mob4A protein; mob1A; mob1 homolog 1A; MOB1 Mps One Binder homolog B; mps one binder kinase activator-like 1A; MOB1, Mps One Binder kinase activator-like 1A; MATS2; MOBKL1A; MGC33910
• Gene ID: 92597
• mRNA Refseq: NM_001244766
• Protein Refseq: NP_001231695
• MIM: 609282
• UniProt ID: Q7L9L4
• Chromosome Location: 4q13.3
• Pathway: Signal Transduction, organism-specific biosystem; Signaling by Hippo, organism-specific biosystem
• Function: kinase activator activity; kinase binding; metal ion binding; protein binding