"CCL5" Related Products

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Recombinant Human Chemokine (C-C Motif) Ligand 5

Cat. No.: CCL5-301H
Product Overview: Recombinant Human Rantes produced in E.Coli is a single, non-glycosylated polypeptide chain containing 68 amino acids and having a molecular mass of 7809.2 Dalton.
Description: Chemokine (C-C motif) ligand 5 (also CCL5) is a protein which in humans is encoded by the CCL5 gene.[1] It is also known as RANTES (Regulated upon Activation, Normal T-cell Expressed, and Secreted).
Species: Human
Source: E.coli
Form: Lyopohilized with no additives.
Purity: Purity Greater than 98% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Bio-activity: rHuRantes is fully biologically active when compared to standard. The activity is determined by the chemoattract of human blood monocytes at a concentration between 1-8 ng/ml.
Physical Appearance: Sterile Filtered white lyophilized (freeze-dried) powder.
Solubility: Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg"s/ml, which can be further diluted into other aqueous solutions.
Purity Greater than 98% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Protein Content determined by: UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Endotoxin Level: Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Amino acid sequence: SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
Storage: Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
Gene Name: CCL5 chemokine (C-C motif) ligand 5 [ Homo sapiens ]
Official Symbol: CCL5
Synonyms: CCL5; chemokine (C-C motif) ligand 5; SISd; beta-chemokine RANTES; EoCP; RANTES; TCP228; MGC17164; SCYA5; RANTES; TCP228; D17S136E; MGC17164; chemokine (C-C motif) ligand 5; regulated upon activation; normally T-expressed; and presumably secrete; presumably secreted; small inducible cytokine A5; small inducible cytokine A5 (RANTES); small inducible cytokine subfamily A (Cys-Cys); member 5; Small-inducible cytokine A5; Small-inducible cytokine A5; T cell-specific protein P228; Eosinophil-chemotactic cytokine; RANTES(3-68); RANTES(4-68); T-cell specific RANTES protein; T-cell-specific protein RANTES; SIS-delta
Gene ID: 6352
mRNA Refseq: NM_002985
Protein Refseq: NP_002976
MIM: 187011
UniProt ID: P13501
Chromosome Location: 17q11.2-q12
Pathway: Chemokine signaling pathway; Cytokine-cytokine receptor interaction; Epithelial cell signaling in Helicobacter pylori infection; Prion diseases; Toll-like receptor signaling pathway; Signaling by GPCR
Function: chemoattractant activity; chemokine activity; signal transducer activity

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