Recombinant Mouse Ccl6 protein, His-tagged

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Recombinant Mouse Ccl6 protein, His-tagged

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Cat.No. : Ccl6-3993M
Product Overview : Recombinant Mouse Ccl6 (Gly22-Ala116) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).
Description : Chemokine (C-C motif) ligand 6 (CCL6), a member of the CC chemokine family, was initially identified as a transcript that is induced in bone marrow cells upon stimulation with GM­CSF. CCL6 has only been identified in rodents, A human homologue for mouse CCL6 has not been identified.  The mCCL6 cDNA encodes a 116 amino acid residue precursor protein with a hydrophobic signal peptide that is cleaved to yield a 95 amino acid residue mature protein. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, where it is strongly induced upon GM­CSF stimulation. Mouse CCL6 expression was also shown to be strongly induced by IL-4 in mouse macrophages and by cytokine IL­13 in mouse lung. Mouse CCL6 is located on chromosome 11. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.
Source : HEK293
Species : Mouse
Tag : His
Predicted N Terminal : Gly22
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 11.4 kDa. The protein migrates as 14 kDa under reducing (R) condition (SDS-PAGE).
Protein length : Gly22-Ala116
Endotoxin : Less than 1.0 EU per μg by the LAL method.
Purity : >90% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.
SDS-PAGE of Ccl6-3993M :

Mouse CCL6, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

Gene Name : Ccl6
Official Symbol : Ccl6
Synonyms : CCL6; chemokine (C-C motif) ligand 6; C-C motif chemokine 6; CC chemokine C10; small inducible cytokine A6; small-inducible cytokine A6; c10; MRP-1; Scya6
Gene ID : 20305
mRNA Refseq : NM_009139
Protein Refseq : NP_033165
UniProt ID : P27784

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