||FGF7 contains a polyhistidine tag at C-terminus and has a calculated MW of 18.9 kDa after removal of signal peptide.
||Fibroblast Growth Factor 7 (FGF7), also known as Keratinocyte Growth Factor (KGF), is a paracrine-acting, epithelial mitogen produced by cells of mesenchymal origin. It is a member of the fibroblast growth factor (FGF) family, and acts exclusively through a subset of FGF receptor isoforms (FGFR2b) expressed predominantly by epithelial cells. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells.
||Recombinant Human Fibroblast Growth Factor 7, Cys33?CThr194 (Accession NP_002000.1) was expressed in HEK293.
||Bulk protein in a 0.22 μm filtered solution of PBS, pH7.4 and delivered as liquid formulation or lyophilized powder. Normally 5-8% trehalose and mannitol are added as protectants before lyophilization.
||>97% purity as determined by SDS-PAGE of reduced FGF7.
||Less than 0.01ng endotoxin per μg FGF7.
||Store at -80°C upon received. Avoid repeated freeze-thaw cycles.