"FGF7" Related Products

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Recombinant Human Fibroblast Growth Factor 7, His-tagged

Cat. No.: FGF7-594H
Product Overview: FGF7 contains a polyhistidine tag at C-terminus and has a calculated MW of 18.9 kDa after removal of signal peptide.
Description: Fibroblast Growth Factor 7 (FGF7), also known as Keratinocyte Growth Factor (KGF), is a paracrine-acting, epithelial mitogen produced by cells of mesenchymal origin. It is a member of the fibroblast growth factor (FGF) family, and acts exclusively through a subset of FGF receptor isoforms (FGFR2b) expressed predominantly by epithelial cells. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells.
Source: Recombinant Human Fibroblast Growth Factor 7, Cys33?CThr194 (Accession NP_002000.1) was expressed in HEK293.
Species: Human
Form: Bulk protein in a 0.22 μm filtered solution of PBS, pH7.4 and delivered as liquid formulation or lyophilized powder. Normally 5-8% trehalose and mannitol are added as protectants before lyophilization.
Purity: >97% purity as determined by SDS-PAGE of reduced FGF7.
Endotoxin: Less than 0.01ng endotoxin per μg FGF7.
Storage: Store at -80°C upon received. Avoid repeated freeze-thaw cycles.
Gene Name: FGF7 fibroblast growth factor 7 [ Homo sapiens ]
Official Symbol: FGF7
Synonyms: FGF7; fibroblast growth factor 7; KGF; HBGF-7; FGF-7; keratinocyte growth factor; heparin-binding growth factor 7; fibroblast growth factor 7 (keratinocyte growth factor); OTTHUMP00000162252
Gene ID: 2252
mRNA Refseq: NM_002009
Protein Refseq: NP_002000
MIM: 148180
UniProt ID: P21781
Chromosome Location: 15q21.2
Pathway: MAPK signaling pathway; Melanoma; Prostate cancer; Regulation of actin cytoskeleton; Signaling by FGFR
Function: growth factor activity; chemoattractant activity; heparin binding; type 2 fibroblast growth factor receptor binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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