Recombinant Human Insulin-Like Growth Factor 1, GST-tag
Cat.No. : | IGF1-657H |
Product Overview : | IGF1 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain fused to a GST tag and is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IGF1-657H |
Description : | The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH; MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed "sulfation factor," which later became known as "somatomedin" (Daughaday et al., 1972). Three main somatomedins have been characterized: somatomedin C (IGF1), somatomedin A (IGF2; MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986; Rosenfeld, 2003). |
Source : | Human |
Host : | Escherichia Coli. |
Form : | IGF1 is supplied in 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol. |
Physical Appearance : | Sterile Filtered clear solution. |
Storage : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
Gene Name : | IGF1 insulin-like growth factor 1 (somatomedin C) [ Homo sapiens ] |
Official Symbol : | IGF1 |
Synonyms : | IGF1; IGFI; IGF-I; IGF1A; insulin-like growth factor 1; MGF; IGF-IA; IGF-IB; somatomedin-C; OTTHUMP00000195080; OTTHUMP00000195081; OTTHUMP00000195082; OTTHUMP00000195083; OTTHUMP00000195084; mechano growth factor; insulin-like growth factor I; insulin-like growth factor IA; insulin-like growth factor IB |
Gene ID : | 3479 |
mRNA Refseq : | NM_000618 |
Protein Refseq : | NP_000609 |
MIM : | 147440 |
UniProt ID : | P05019 |
Chromosome Location : | 12q23.2 |
Pathway : | Adipogenesis; Aldosterone-regulated sodium reabsorption; Androgen Receptor Signaling Pathway; Apoptosis; Diabetes pathways; Dilated cardiomyopathy; Endochondral Ossification; Focal Adhesion; Formation of Platelet plug; Glioma; Hemostasis; Hypertrophic cardiomyopathy (HCM); Id Signaling Pathway; Long-term depression; Melanoma; MicroRNAs in cardiomyocyte hypertrophy; Oocyte meiosis; Pathways in cancer; Platelet Activation; Platelet degranulation; Progesterone-mediated oocyte maturation; Prostate cancer; Response to elevated platelet cytosolic Ca2+; mTOR signaling pathway; p53 signaling pathway |
Function : | growth factor activity; hormone activity; insulin receptor binding; insulin-like growth factor receptor binding; integrin binding; protein binding |
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◆ Lysates | ||
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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