Recombinant Mouse Interleukin 1 Beta Il1b-462M

Recombinant Mouse Interleukin 1 Beta

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Mouse Interleukin 1 Beta

Recombinant Mouse Interleukin 1 Beta

Il1b Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat. No. : Il1b-462M
Product Overview : Recombinant mouse IL-1μ is a non-glycosylated single chain 17,394 Da protein containing 152 amino acid residues.
Description : Interleukin-1beta (IL-1μ) is a proinflammatory cytokine produced in response to inflammatory agents by a variety of cells, including monocytes, macrophages, and dendritic cells (DCs). IL-1μ and IL-1μ are two distinct and independently regulated gene products that comprise IL-1 and signal through the Type 1 IL-1 receptor (IL-1R1). Although IL-1μ is cell associated and IL-1μ is secreted, they have nearly identical biological activity in that they induce adhesion molecule expression on epithelial cells, control fever induction, and play a role in arthritis and septic shock. Signaling activated by the IL-1R1 promotes these activities through a MYD88 signaling pathway similar to those associated with Toll receptors.
Species : Mouse
Source : E.coli
Form : Lyophilized from 10 mM NaP, pH 7.
Purity : Purity Greater than 97% as determined by: Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Bio-activity : Mouse IL-1μ is fully biologically active when compared to a standard. The ED50, as determined by the dose-dependent proliferation of mouse D10S cells, is 1.82 pg/ml.
Physical Appearance : Sterile Filtered white lyophilized (freeze-dried) powder.
Solubility : It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.
Purity Greater than 97% as determined by : Analysis by RP-HPLC. Reducing and non-reducing SDS-PAGE.
Protein Content determined by : UV spectroscopy at 280 nm. Analysis by RP-HPLC calibrated against a known standard. Quantitation on SDS-PAGE against a known standard.
Endotoxin Level : Endotoxin level is <0.01ng/ug or <0.1EU/ug.
Amino acid sequence : VPIRQLHYR LRDEQQKSLV LSDPYELKAL HLNGQNINQQ VIFSMSFVQG EPSNDKIPVA LGLKGKNLYL SCVMKDGTPT LQLESVDPKQPKKKMEKRF VFNKIEVKSK VEFESAEFPN WYISTSQAEH KPVFLGNNSGQDIIDFTMES VS
Storage : Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
PDB rendering based on 31BI. :

Gene Name : Il1b interleukin 1 beta [ Mus musculus ]
Official Symbol : Il1b
Synonyms : RP23-384K11.2; IL-1beta; Il-1b; Catabolin; IL-1; Lymphocyte-activating factor; LAF; Endogenous Pyrogen; EP; Leukocyte Endogenous Mediator; LEM; Mononuclear Cell Factor; MCF; IL1F2; Interleukin-1 beta; pro-interleukin-1-beta; Interleukin-1 beta precursor; preinterleukin 1 beta
Gene ID : 16176
mRNA Refseq : NM_008361
Protein Refseq : NP_032387
UniProt ID : P10749
Chromosome Location : 2 73.0 cM
Pathway : Apoptosis; Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; MAPK signaling pathway; Toll-like receptor signaling pathway; Type I diabetes mellitus
Function : cytokine activity; growth factor activity; interleukin-1 receptor binding

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy