Native Human Myoglobin
Cat.No. : | MB-4460H |
Product Overview : | Human Myoglobin produced in Human Cardiac Tissues having a molecular mass of 17.5kDa. Myoglobin is released from recently injured myocardial cells within a few hours of Infarction. Peak levels are reached more quickly than CK-MB or Troponin complex. |
- Specification
- Gene Information
- Related Products
Description : | Myoglobin is a member of the globin superfamily and can be found in skeletal and cardiac muscles. It is a haemoprotein that contributs to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. Myoglobin has a single-chain globular structure of 153 amino acids, containing a heme prosthetic group (iron-containing porphyrin) in the core around which the remaining apoprotein folds. Myoglobin has 8 alpha helices and a hydrophobic core. Myoglobinμs molecular weight is 16.7 kDa, and it is the primary oxygen-carrying pigment of muscle tissues. The binding of oxygen in myoglobin is different from the cooperative oxygen binding in hemoglobin, since positive collaboration is a property of multimeric/oligomeric proteins only. Instead, the binding of oxygen by myoglobin is uninfluenced by the oxygen pressure in the surrounding tissue. Myoglobin is frequently referred to as having an "instant binding tenacity" to oxygen given its hyperbolic oxygen dissociation curve. |
Source : | Human Cardiac Tissues. |
Species : | Human |
Form : | The protein solution is in 0.05M phosphate buffer containing 0.15M NaCl and 0.09% NaN3 pH 7.5. Filtered through a 0.2μM membrane. |
Molecular Mass : | 17.5kDa |
Purity : | Greater than 96.0%. |
Stability : | Human Myoglobin should be stored at 2-8°C. |
Gene Name : | MB myoglobin [ Homo sapiens ] |
Official Symbol : | MB |
Synonyms : | MB; myoglobin; PVALB; MGC13548; |
Gene ID : | 4151 |
mRNA Refseq : | NM_005368 |
Protein Refseq : | NP_005359 |
MIM : | 160000 |
UniProt ID : | P02144 |
Chromosome Location : | 22q13.1 |
Function : | heme binding; metal ion binding; oxygen binding; oxygen transporter activity; |
Products Types
◆ Recombinant Protein | ||
MB-25B | Active Native Bovine Myoglobin | +Inquiry |
MB-5391M | Recombinant Mouse MB Protein, His (Fc)-Avi-tagged | +Inquiry |
MB-01H | Recombinant Human MB Protein, His-tagged | +Inquiry |
MB-1148H | Recombinant Horse MB Protein, His-tagged | +Inquiry |
MB-3257R | Recombinant Rat MB Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
Mb-8229M | Native Mouse Myoglobin | +Inquiry |
Mb-8232R | Native Rat Myoglobin | +Inquiry |
MB-237C | Native Dog Myoglobin | +Inquiry |
◆ Lysates | ||
MB-4446HCL | Recombinant Human MB 293 Cell Lysate | +Inquiry |
MB-4445HCL | Recombinant Human MB 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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