| Species : |
Human |
| Source : |
Human |
| Tag : |
Non |
| Protein Length : |
1-357 a.a. |
| Description : |
NRXN3 is a single-pass type I membrane protein which belongs to the neurexin family. It contains one laminin G-like domain. It is a neuronal cell surface protein that may be involved in cell recognition and cell adhesion. Neurexins are a family of proteins that function in the vertebrate nervous system as cell adhesion molecules and receptors. |
| Form : |
Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
| Purity : |
> 95 % as determined by SDS-PAGE |
| Bio-activity : |
Measured by the ability of the immobilized protein to support the adhesion of C6 Rat brain glial cells. When 5x104 cells/well are added to NRXN3 coated plates (0.8 μg/mL and 100 μL/well), approximately 30%-50% will adhere specifically after 60 minutes at 37°C |
| Endotoxin : |
< 1.0 EU per μg of the protein as determined by the LAL method |
| Stability : |
Samples are stable for up to twelve months from date of receipt at -70°C. |
| Predicted N terminal : |
Ser 36 |
| Molecular Mass : |
The secreted recombinant human NRXN3/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 563 amino acids and predictes a molecular mass of 61.6 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh NRXN3/Fc monomer is approximately 75-85 kDa due to glycosylation. |
| Storage : |
Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
