"SUMF1" Related Products

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Recombinant Human Sulfatase Modifying Factor 1, His-tagged

Cat. No.: SUMF1-1539H
Product Overview: Recombinant human SUMF1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Description: SUMF1 (Sulfatase-modifying factor 1) belongs to the SUMF family. SUMF1 is an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder.
Form: Liquid. In 20mM Tris-HCl, pH8.0, 2M Urea, 20%Glycerol, 2mM DTT
Molecular Weight: 34.1kDa (304aa)
Purity: > 85% by SDS - PAGE
Concentration: 0.5mg/ml (determined by Bradford assay)
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MVPIPAGVFT MGTDDPQIKQ DGEAPARRVT IDAFYMDAYE VSNTEFEKFV NSTGYLTEAE KFGDSFVFEG MLSEQVKTNI QQAVAAAPWW LPVKGANWRH PEGPDSTILH RPDHPVLHVS WNDAVAYCTW AGKRLPTEAE WEYSCRGGLH NRLFPWGNKL QPKGQHYANI WQGEFPVTNT GEDGFQGTAP VDAFPPNGYG LYNIVGNAWE WTSDWWTVHH SVEETLNPKG PPSGKDRVKK GGSYMCHRSY CYRYRCAARS QNTPDSSASN LGFRCAADRL PTMD
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways: Lysosome
Gene Name: SUMF1 sulfatase modifying factor 1 [ Homo sapiens ]
Official Symbol: SUMF1
Synonyms: SUMF1; FGE; UNQ3037; AAPA3037; MGC131853; MGC150436; sulfatase-modifying factor 1; OTTHUMP00000115300; OTTHUMP00000207086; OTTHUMP00000207089; FGly-generating enzyme; C-alpha-formylglycine-generating enzyme 1; sulfatase modifying factor 1; OTTHUMP00000207088; EC 1.8.99
Gene ID: 285362
mRNA Refseq: NM_182760
Protein Refseq: NP_877437
MIM: 607939
UniProt ID: Q8NBK3
Chromosome Location: 3p26.1
Function: binding; metal ion binding; oxidoreductase activity; protein homodimerization activity

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