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Active Recombinant Mouse Vascular Endothelial Growth Factor A

Cat.No. : Vegfa-582M
Product Overview : Recombinant Mouse VEGF-120 is a truncated version of Mouse VEGF-165. Mouse VEGF-120 is a homodimer with a molecular weight of 28.2 kDa
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  • Gene Information
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Cat. No. : Vegfa-582M
Description : Vascular endothelial growth factor A (VEGF-A) is a protein that in humans is encoded by the VEGFA gene. This gene is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and encodes a protein that is often found as a disulfide linked homodimer. As its name implies, VEGF-A activity has been studied mostly on cells of the vascular endothelium, although it does have effects on a number of other cell types.
Species : Mouse
Source : E.coli
Form : Lyophilized with no additives.
Purity : Purity Greater than 97% as determined by: Reducing and non-reducing SDS-PAGE. Analytical HPLC.
Bio-activity : In process
Physical Appearance : Sterile Filtered white lyophilized (freeze-dried) powder.
Solubility : It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 ?C 0.5 mgμs/ml, which can be further diluted into other aqueous solutions.
Purity Greater than 97% as determined by : Reducing and non-reducing SDS-PAGE. Analytical HPLC
Protein Content determined by : UV spectroscopy at 280 nm. Quantitation on SDS-PAGE against a known standard.
Endotoxin Level : Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.
Amino acid sequence : APTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVPTSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKCDKRPR R
Storage : Lyophilized product is very stable at -20 degrees. Reconstituted material should be aliquoted and frozen at -20. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.
Gene Name : Vegfa vascular endothelial growth factor A [ Mus musculus ]
Official Symbol : Vegfa
Synonyms : Vegfa; vascular endothelial growth factor A;Vpf; Vegf; Vegf-a; Vegf120; Vegf164; VEGF120; VPF; Vegf188; OTTMUSP00000017463; VEGF164; OTTMUSP00000017464; VEGF-A; OTTMUSP00000022243; vascular permeability factor; VEGF188; MGC70609; MVCD1; VEGF; Vascular permeability factor; vascular endothelial growth factor; vascular endothelial growth factor isoform VEGF165
Gene ID : 22339
mRNA Refseq : NM_001025250
Protein Refseq : NP_001020421
UniProt ID : Q00731
Chromosome Location : 17 C; 17 24.2 cM
Pathway : Bladder cancer; Focal adhesion; Cytokine-cytokine receptor interaction; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; VEGF signaling pathway; mTOR signaling pathway
Function : growth factor activity; heparin binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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How does VEGFA protein relate to other biomarkers? 05/28/2022

Studies have shown that there is an association between the expression level of VEGFA protein and other biomarkers, for example, it can be associated with indicators such as tumor cell differentiation, metastatic capacity, and prognosis.

How to harness the activity of VEGFA protein for disease treatment? 05/14/2022

At present, a variety of drugs have been developed to target the VEGFA protein and its related signaling pathway, including inhibiting its expression and inhibiting its binding to receptors, etc., for the treatment of tumors and other vascular-related diseases.

What is the role of VEGFA protein in tumor angiogenesis? 09/24/2020

VEGFA protein plays a key role in tumor angiogenesis, promoting tumor growth and metastasis by stimulating endothelial cell proliferation, migration, and vascular network formation.

How well is the VEGFA protein expressed in different tissues and organs? 07/09/2020

The expression of VEGFA protein in different tissues and organs is different, and it is expressed in tumor tissue, cardiovascular system and other tissues and organs, and the expression level may be affected by many factors.

What is the relationship between the expression level of VEGFA protein and the degree of tumor malignancy? 03/26/2020

Studies have shown that the expression level of VEGFA protein is related to the degree of malignancy of the tumor, and the high expression of VEGFA protein often indicates that the tumor is more aggressive.

How about the fuction of VEGFA protein in cardiovascular disease? 01/10/2019

VEGFA protein plays an important role in cardiovascular disease by regulating endothelial cell function, promoting vascular repair and maintaining cardiovascular system homeostasis.

Customer Reviews (2)

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Reviews
04/21/2021

    VEGFA's catalytic activity is so strong that it can adapt even in the face of complex chemical reactions.

    03/09/2020

      VEGFA they produced was highly active and the experimental effect was obvious.

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