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Recombinant Human PRDX3

Cat. No.: PRDX3-1025H
Product Overview: RecombinantHuman PRDX3 protein was expressed in E.coli. MW=21.6 kDa.
Description: PRDX3 is a growing peroxidase family, whose mammalian membershave been known to connect with cell proliferation, differentiation, andapoptosis. Many isoforms collected in accordance to the amino acid sequencehomology, particularly amino-terminal region containing active site cysteineresidue, and the thiol-specific antioxidant activity, distribute throughoutall the kingdoms.
Source: E. coli
Species: Human
Molecular Weight: 21.6kDa
Researchtopic: Oxidativestress
Packaging size: 1.0 U(0.83mg)
Specific activity: 1.20 U/mg(Unit definition: One unit will cause the oxidation of 1.0 μmole of NADPH at25°C at pH 7.5).
Form: Lyophilized powder containing HEPES, pH7.0.
Reconstitution: Reconstitute with 0.83ml distilled water to obtain1.0mg/ml.
Gene Name: PRDX3 peroxiredoxin3 [ Homo sapiens ]
Official Symbol: PRDX3
Synonyms: PRDX3; peroxiredoxin 3; AOP1; MER5; AOP-1; SP-22; HBC189;PRO1748; prx-III; MGC24293; MGC104387; thioredoxin-dependent peroxide reductase,mitochondrial; peroxiredoxin-3; peroxiredoxin III; protein MER5 homolog;antioxidant protein 1; EC 1.11.1.15; OTTHUMP00000020590
Gene ID: 10935
mRNA Refseq: NM_006793
Protein Refseq: NP_006784
MIM: 604769
UniProt ID: P30048
Chromosome Location: 10q25-q26
Pathway: Selenium Pathway; Validated targets ofC-MYC transcriptional activation
Function: alkyl hydroperoxide reductase activity;cysteine-type endopeptidase inhibitor activity involved in apoptotic process;identical protein binding; kinase binding; oxidoreductase activity;peroxidase activity; peroxiredoxin activity; protein C-terminus binding;protein binding; protein kinase binding

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