Recombinant Human PRDX3

• Cat.No.: PRDX3-1025H
• Product Overview: RecombinantHuman PRDX3 protein was expressed in E.coli. MW=21.6 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: PRDX3 is a growing peroxidase family, whose mammalian membershave been known to connect with cell proliferation, differentiation, andapoptosis. Many isoforms collected in accordance to the amino acid sequencehomology, particularly amino-terminal region containing active site cysteineresidue, and the thiol-specific antioxidant activity, distribute throughoutall the kingdoms.
• Molecular Weight: 21.6kDa
• Researchtopic: Oxidativestress
• Packaging size: 1.0 U(0.83mg)
• Specific activity: 1.20 U/mg(Unit definition: One unit will cause the oxidation of 1.0 μmole of NADPH at25°C at pH 7.5).
• Form: Lyophilized powder containing HEPES, pH7.0.
• Reconstitution: Reconstitute with 0.83ml distilled water to obtain1.0mg/ml.

Gene Information

• Gene Name: PRDX3 peroxiredoxin3 [ Homo sapiens ]
• Official Symbol: PRDX3
• Synonyms: PRDX3; peroxiredoxin 3; AOP1; MER5; AOP-1; SP-22; HBC189;PRO1748; prx-III; MGC24293; MGC104387; thioredoxin-dependent peroxide reductase,mitochondrial; peroxiredoxin-3; peroxiredoxin III; protein MER5 homolog;antioxidant protein 1; EC 1.11.1.15; OTTHUMP00000020590
• Gene ID: 10935
• mRNA Refseq: NM_006793
• Protein Refseq: NP_006784
• MIM: 604769
• UniProt ID: P30048
• Chromosome Location: 10q25-q26
• Pathway: Selenium Pathway; Validated targets ofC-MYC transcriptional activation
• Function: alkyl hydroperoxide reductase activity;cysteine-type endopeptidase inhibitor activity involved in apoptotic process;identical protein binding; kinase binding; oxidoreductase activity;peroxidase activity; peroxiredoxin activity; protein C-terminus binding;protein binding; protein kinase binding