"GH1" Related Products

Recombinant Human GH1 (1-217aa)

Cat. No. : GH1-241H
Product Overview : Human GH1 (P01241, 1 a.a.-217 a.a.) full-length recombinant protein expressed in Escherichia coli.
Description : Somatotropin is a protein that in humans is encoded by the GH1 gene. The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones that play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement thought to have evolved by a series of gene duplications.
Sequence : MATGSRTSLL LAFGLLCLPW LQEGSAFPTI PLSRLFDNAM LRAHRLHQLA FDTYQEFEEA YIPKEQKYSF LQNPQTSLCF SESIPTPSNR EETQQKSNLE LLRISLLLIQ SWLEPVQFLR SVFANSLVYG ASDSNVYDLL KDLEEGIQTL MGRLEDGSPR TGQIFKQTYS KFDTNSHNDD ALLKNYGLLY CFRKDMDKVE TFLRIVQCRS VEGSCGF
Theoretical MW : 22
Form : Lyophilized
Preparation Method : Escherichia coli expression system
Purity : > 95% by SDS-PAGE and HPLC
Endotoxin Level : < 0.1 ng/ug (1 EU/ug)
Activity : The ED50 was determined by the dose-dependent cell proliferation assay using the rat lymphoma, Nb2-11, and was found to be in the range of 0.1 ng/mL.
Application : SDS-PAGE
Storage Buffer : Lyophilized from 0.005 mM NaHCO3 solution pH 10
Storage : Store at -20°C on dry atmosphere for 2 years. After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months. Aliquot to avoid repeated freezing and thawing.
Unitprot ID : P01241
Pathways : Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Neuroactive ligand-receptor interaction
PDBrendering based on 1a22. :

Gene Name : GH1 growth hormone 1 [ Homo sapiens ]
Official Symbol : GH1
Synonyms : GH; GH-N; GHN; hGH-N; Growth hormone; Pituitary growth hormone; growth hormone 1; GH1; IGHD1B; Somatotropin; hGH
Gene ID : 2688
mRNA Refseq : NM_000515
Protein Refseq : NP_000506
MIM : 139250
Chromosome Location : 17q24.2
Function : growth factor activity; growth hormone activity; growth hormone receptor binding; prolactin receptor binding; protein binding

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