Recombinant Human AKT2, GST-tagged AKT2-802H

Recombinant Human AKT2, GST-tagged

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Recombinant Human AKT2, GST-tagged

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Cat.No. : AKT2-802H
Product Overview : Recombinant Human AKT2, fused with GST-tag at N-terminal, was expressed in Sf9 cells.
Description : This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.
Source : Sf9 cells
Species : Human
Tag : GST
Form : Liquid
Bio-activity : The specific activity was determined to 43 nmol/min/mg as per Activity Assay Protocol.
Molecular Mass : 85 kDa
Purity : >90% by densitometry
Applications : Functional Study; SDS-PAGE
Storage : Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol)
Gene Name : AKT2 v-akt murine thymoma viral oncogene homolog 2 [ Homo sapiens ]
Official Symbol : AKT2
Synonyms : AKT2; v-akt murine thymoma viral oncogene homolog 2; PKBB; PRKBB; PKBBETA; RAC-BETA; AKT2 kinase; rac protein kinase beta; Murine thymoma viral (v-akt) homolog-2; EC 2.7.11.1; RAC-beta serine/threonine-protein kinase; RAC-PK-beta; Protein kinase Akt-2; Protein kinase B, beta; PKB beta
Gene ID : 208
mRNA Refseq : NM_001626
Protein Refseq : NP_001617
MIM : 164731
UniProt ID : P31751
Chromosome Location : 19q13.1-q13.2
Pathway : AKT phosphorylates targets in the cytosol; AMPK signaling; Activation of BH3-only proteins
Function : ATP binding; kinase activity; protein binding; protein serine/threonine kinase activity

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