Recombinant Human BDNF


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Recombinant Human BDNF

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Cat. No. : BDNF-003H
Product Overview : Human BDNF (P23560, 129 a.a. - 247 a.a.) partial recombinant protein expressed in Escherichia coli.
Description : Brain-derived neurotrophic factor, also known as BDNF, is a protein that, in humans, is encoded by the BDNF gene.BDNF is a member of the "neurotrophin" family of growth factors, which are related to the canonical "Nerve Growth Factor", NGF. Neurotrophic factors are found in the brain and the periphery.
Theoretical MW (kDa) : 14
Form : Lyophilized
Preparation Method : E. coli expression system
Purity : > 97% by SDS-PAGE and HPLC
Endotoxin Level : < 0.1 ng/ug (1 EU/ug)
Activity : The ED50 was determined by the dose-dependent proliferation of rat C6 cells, and was found to be in the range of 0.5 ug/mL.
Application : SDS-PAGE
Storage Buffer : Lyophilized from citric acid, pH 5.7
Storage : Store at -20°C on dry atmosphere for 2 years.After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.Aliquot to avoid repeated freezing and thawing.
Unitprot ID : P23560
Pathways : Huntington"s disease; MAPK signaling pathway; Neurotrophin signaling pathway
PDB rendering basedon 1bnd :

Publication :
Gene Name : BDNF brain-derived neurotrophic factor [ Homo sapiens ]
Official Symbol : BDNF
Synonyms : BDNF; brain-derived neurotrophic factor; MGC34632; abrineurin; neurotrophin; OTTHUMP00000232005; OTTHUMP00000232006; OTTHUMP00000232013; OTTHUMP00000232014; OTTHUMP00000232015; OTTHUMP00000232016; OTTHUMP00000232018; OTTHUMP00000232019; OTTHUMP00000232020; OTTHUMP00000232021; OTTHUMP00000232022; OTTHUMP00000232039; OTTHUMP00000232040; OTTHUMP00000232041; OTTHUMP00000232043
Gene ID : 627
mRNA Refseq : NM_001143806
Protein Refseq : NP_001137278
MIM : 113505
Chromosome Location : 11p13
Function : Growth factor activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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