Recombinant Human BDNF BDNF-003H

Recombinant Human BDNF

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Recombinant Human BDNF

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Cat. No. : BDNF-003H
Product Overview : Human BDNF (P23560, 129 a.a. - 247 a.a.) partial recombinant protein expressed in Escherichia coli.
Description : Brain-derived neurotrophic factor, also known as BDNF, is a protein that, in humans, is encoded by the BDNF gene.BDNF is a member of the "neurotrophin" family of growth factors, which are related to the canonical "Nerve Growth Factor", NGF. Neurotrophic factors are found in the brain and the periphery.
Sequence : HS DPARRGELSV CDSISEWVTA ADKKTAVDMS GGTVTVLEKV PVSKGQLKQY FYETKCNPMG YTKEGCRGID KRHWNSQCRT TQSYVRALTM DSKKRIGWRF IRIDTSCVCT LTIKRGR
Theoretical MW (kDa) : 14
Form : Lyophilized
Preparation Method : E. coli expression system
Purity : > 97% by SDS-PAGE and HPLC
Endotoxin Level : < 0.1 ng/ug (1 EU/ug)
Activity : The ED50 was determined by the dose-dependent proliferation of rat C6 cells, and was found to be in the range of 0.5 ug/mL.
Application : SDS-PAGE
Storage Buffer : Lyophilized from citric acid, pH 5.7
Storage : Store at -20°C on dry atmosphere for 2 years.After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.Aliquot to avoid repeated freezing and thawing.
Unitprot ID : P23560
Pathways : Huntington"s disease; MAPK signaling pathway; Neurotrophin signaling pathway
PDB rendering basedon 1bnd :

Publication :
Gene Name : BDNF brain-derived neurotrophic factor [ Homo sapiens ]
Official Symbol : BDNF
Synonyms : BDNF; brain-derived neurotrophic factor; MGC34632; abrineurin; neurotrophin; OTTHUMP00000232005; OTTHUMP00000232006; OTTHUMP00000232013; OTTHUMP00000232014; OTTHUMP00000232015; OTTHUMP00000232016; OTTHUMP00000232018; OTTHUMP00000232019; OTTHUMP00000232020; OTTHUMP00000232021; OTTHUMP00000232022; OTTHUMP00000232039; OTTHUMP00000232040; OTTHUMP00000232041; OTTHUMP00000232043
Gene ID : 627
mRNA Refseq : NM_001143806
Protein Refseq : NP_001137278
MIM : 113505
Chromosome Location : 11p13
Function : Growth factor activity

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