"CLU" Related Products

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Human Clusterin

Cat. No.: CLU-3661H
Product Overview: Native protein purified from human plasma.
Description: Clusterin is a 75-80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene.
Source: native
Species: Human
Form: Filtered (0,4 μm) and lyophilized from PBS, pH 7.5.
Research topic: Others; Renal disease; Sepsis
Purity: >95%
Reconstitution: Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely.
Applications: ELISA; Western blotting
Quality Control Test: BCA to determine quantity of the protein; SDS-PAGE to determine purity of the protein
Storage: Store lyophilized protein at -20°C. Lyophilized protein remains stable until the expiry date when stored at -20°C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at -80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after one week at 4°C.
Gene Name: CLU clusterin [ Homo sapiens ]
Official Symbol: CLU
Synonyms: CLU; clusterin; CLI; AAG4; APOJ; KUB1; SGP2; SGP-2; SP-40; TRPM2; TRPM-2; MGC24903; apo-J; NA1/NA2; apolipoprotein J; OTTHUMP00000128311; OTTHUMP00000225247; OTTHUMP00000225248; OTTHUMP00000225249; ku70-binding protein 1; sulfated glycoprotein 2; aging-associated protein 4; complement lysis inhibitor; complement cytolysis inhibitor; complement-associated protein SP-40,40; testosterone-repressed prostate message 2
Gene ID: 1191
mRNA Refseq: NM_203339
Protein Refseq: NP_976084
MIM: 185430
UniProt ID: P10909
Chromosome Location: 8p21-p12
Pathway: Formation of Platelet plug; Hemostasis; Platelet Activation; Platelet degranulation; Response to elevated platelet cytosolic Ca2+; Validated targets of C-MYC transcriptional repression
Function: NOT ATPase activity; misfolded protein binding; ubiquitin protein ligase binding; ubiquitin protein ligase binding

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