Recombinant Human MGP, His-tagged
Cat.No. : | MGP-3641H |
Product Overview : | Recombinant human MGP protein, fused to His-tag at N-terminus, was expressed in E.coli and denatured using detergent during a conventional chromatography purification process (20-96aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | MGP-3641H |
Description : | MGP, also known as Matrix Gla protein, is a protein involved in regulating calcification in the extracellular matrix, in particular in cartilage and arteries. MGP is a vitamin K-dependent protein, and contains five to six residues of Gla, a Ca2+ binding amino acid requiring vitamin K-dependent gamma carboxylase for its formation. It is found in human bone extracts, likely formed by COOH-terminal processing by carboxypeptidase B-like enzymatic activity. |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol |
Molecular Weight : | 11.8 kDa (98aa) |
Purity : | > 90% by SDS - PAGE |
Concentration : | 1.0 mg/ml (determined by Bradford assay) |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MYESHESMES YELNPFINRR NANTFISPQQ RWRAKVQERI RERSKPVHEL NREACDDYRL CERYAMVYGY NAAYNRYF |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | Endochondral Ossification; Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
Gene Name : | MGP matrix Gla protein [ Homo sapiens ] |
Official Symbol : | MGP |
Synonyms : | MGP; NTI; GIG36; MGLAP; matrix Gla protein; OTTHUMP00000239335; OTTHUMP00000239337; cell growth-inhibiting gene 36 protein |
Gene ID : | 4256 |
mRNA Refseq : | NM_000900 |
Protein Refseq : | NP_000891 |
MIM : | 154870 |
UniProt ID : | P08493 |
Chromosome Location : | 12p12.3 |
Function : | calcium ion binding; extracellular matrix structural constituent; structural constituent of bone |
Products Types
◆ Recombinant Protein | ||
MGP-5542M | Recombinant Mouse MGP Protein, His (Fc)-Avi-tagged | +Inquiry |
MGP-2586R | Recombinant Rhesus Macaque MGP Protein, His (Fc)-Avi-tagged | +Inquiry |
MGP-5306H | Recombinant Human MGP Protein, GST-tagged | +Inquiry |
MGP-3331R | Recombinant Rat MGP Protein, His (Fc)-Avi-tagged | +Inquiry |
MGP-95M | Recombinant Mouse Mgp Protein, His-tagged | +Inquiry |
◆ Lysates | ||
MGP-4329HCL | Recombinant Human MGP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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