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Recombinant Human V-Erb-A Erythroblastic Leukemia Viral Oncogene Homolog 4 (avian), GST-tagged

Cat.No. : ERBB4-1126H
Product Overview : Recombinant human ERBB4 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
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  • Gene Information
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Cat. No. : ERBB4-1126H
Description : ERBB4 is a receptor tyrosine kinase that is a member of the epidermal growth factor receptor subfamily. ERBB4 is a single-pass type I transmembrane protein with multiple furin-like cysteine rich domains, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins-2 and -3, heparin-binding EGF-like growth factor and betacellulin.
Biological Activity : 137 pmol/µg×min
Molecular Weight : 102,062 Da
Source : Sf9 insect cells
Species : Human
Appearance : Liquid
Storage : 50 mMTris-HCl, pH 8.0;100 mMNaCl, 5 mM DTT, 15 mM reducedglutathione, 20% glycerol.
Pathways : Calcium signaling pathway; Endocytosis; ErbB signaling pathway
Gene Name : ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) [ Homo sapiens ]
Official Symbol : ERBB4
Synonyms : ERBB4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4; Receptor tyrosine-protein kinase erbB-4; HER4; Tyrosine kinase-type cell surface receptor HER4; p180erbB4; EC 2.7.10.1; MGC138404; avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4; receptor tyrosine-protein kinase erbB-4; v-erb-a erythroblastic leukemia viral oncogene homolog 4; OTTHUMP00000163968; OTTHUMP00000206623; OTTHUMP00000209432
Gene ID : 2066
mRNA Refseq : NM_001042599
Protein Refseq : NP_001036064
MIM : 600543
UniProt ID : Q15303
Chromosome Location : 2q33.3-q34
Function : ATP binding; nucleotide binding; protein binding; receptor activity; receptor signaling protein tyrosine kinase activity; transferase activity; transmembrane receptor protein tyrosine kinase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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