"PGF" Related Products

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Recombinant Human Placental Growth Factor

Cat. No.: PGF-607H
Product Overview: Recombinant human PGF is a 29.7 kDa homodimeric protein consisting of two 131 amino acid polypeptide chains.
Description: PGF is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PGF is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant human PGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 131 amino acid polypeptide chains.
Biological Activity: Determined by its ability to chemoattract human monocytes of using a concentration range of 0.5-10 ng/ml.
Molecular Weight: 29.7 kDa
Source: E. coli
Species: Human
Form: Sterile filtered and lyophilized in a solution containing BSA.
Endotoxin Level: <0.1 ng/μg
Reconstitution: Reconstitute the protein in sterile 20 mM acetic acid to a concentration of 0.1-1.0 μg/μl. The solution can then be diluted into other aqueous buffer.
Appearance: Lyophilized protein
Purity: ≥95% by SDS-PAGE and ≥95% by HPLC
Storage: The lyophilized protein is best-stored desiccated below 0°C. Reconstituted protein should be stored at working aliquots at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HAS or BSA). Prevent freeze/thaw cycles.
Gene Name: PGF placental growth factor [ Homo sapiens ]
Official Symbol: PGF
Synonyms: PGF; placental growth factor; PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760; placenta growth factor; placental growth factor-like; placental growth factor, vascular endothelial growth factor-related protein
Gene ID: 5228
mRNA Refseq: NM_001207012
Protein Refseq: NP_001193941
MIM: 601121
UniProt ID: P49763
Chromosome Location: 14q24.3
Pathway: Bladder cancer; Focal Adhesion; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; Rheumatoid arthritis; Signaling by VEGF; VEGF binds to VEGFR leading to receptor dimerization; VEGF ligand-receptor interactions; VEGFR1 specific signals; mTOR signaling pathway
Function: growth factor activity; heparin binding

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