Recombinant Human Placental Growth Factor
Cat.No. : | PGF-607H |
Product Overview : | Recombinant human PGF is a 29.7 kDa homodimeric protein consisting of two 131 amino acid polypeptide chains. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PGF-607H |
Description : | PGF is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PGF is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant human PGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 131 amino acid polypeptide chains. |
Biological Activity : | Determined by its ability to chemoattract human monocytes of using a concentration range of 0.5-10 ng/ml. |
Molecular Weight : | 29.7 kDa |
Source : | E. coli |
Species : | Human |
Form : | Sterile filtered and lyophilized in a solution containing BSA. |
Endotoxin Level : | <0.1 ng/μg |
Reconstitution : | Reconstitute the protein in sterile 20 mM acetic acid to a concentration of 0.1-1.0 μg/μl. The solution can then be diluted into other aqueous buffer. |
Appearance : | Lyophilized protein |
Purity : | ≥95% by SDS-PAGE and ≥95% by HPLC |
Storage : | The lyophilized protein is best-stored desiccated below 0°C. Reconstituted protein should be stored at working aliquots at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HAS or BSA). Prevent freeze/thaw cycles. |
Gene Name : | PGF placental growth factor [ Homo sapiens ] |
Official Symbol : | PGF |
Synonyms : | PGF; placental growth factor; PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760; placenta growth factor; placental growth factor-like; placental growth factor, vascular endothelial growth factor-related protein |
Gene ID : | 5228 |
mRNA Refseq : | NM_001207012 |
Protein Refseq : | NP_001193941 |
MIM : | 601121 |
UniProt ID : | P49763 |
Chromosome Location : | 14q24.3 |
Pathway : | Bladder cancer; Focal Adhesion; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; Rheumatoid arthritis; Signaling by VEGF; VEGF binds to VEGFR leading to receptor dimerization; VEGF ligand-receptor interactions; VEGFR1 specific signals; mTOR signaling pathway |
Function : | growth factor activity; heparin binding |
Products Types
◆ Recombinant Protein | ||
PGF-0042H | Recombinant Human PGF Protein | +Inquiry |
PGF-417H | Recombinant Human PGF Protein, His-tagged | +Inquiry |
PGF-100H | Active Recombinant Human PGF Protein | +Inquiry |
PGF-099H | Active Recombinant Human PGF Protein | +Inquiry |
PGF-4065R | Recombinant Rat PGF Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PGF-1118MCL | Recombinant Mouse PGF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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