Recombinant Human Distone Deacetylase 4, GST-tagged
Cat.No. : | HDAC4-1592H |
Product Overview : | Recombinant human HDAC4 (612-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | HDAC4-1592H |
Description : | HDAC4 or Histone Deacetylase 4 belongs to class II of the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex that represses transcription when tethered to a promoter. HDAC4 does not bind DNA directly, but through transcription factors MEF2C and MEF2D. Binding of the N terminus of HDAC4 to MEF2C represses MEF2C transcription activity. |
Applications : | HDAC Assay; Western Blot |
Molecular Weight : | 77 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Species : | Human |
Form : | Recombinant protein stored in 50 mM Tris-HCl, PH 7.5, 150 mM NaCI, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
Purity : | >95% |
Concentration : | 0.1 ug/ul |
Specific Activity : | 60 RLU/min/ng |
Sequences : | 612-end |
Storage : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | Cell cycle; Endochondral Ossification; MicroRNAs in cardiomyocyte hypertrophy; Signaling events mediated by HDAC Class I; Signaling events mediated by HDAC Class II; Signaling events mediated by HDAC Class III; Sumoylation by RanBP2 regulates transcriptional repression |
Gene Name : | HDAC4 histone deacetylase 4 [ Homo sapiens ] |
Official Symbol : | HDAC4 |
Synonyms : | HDAC4; histone deacetylase 4; HD4; AHO3; BDMR; HDACA; HA6116; HDAC-4; HDAC-A; KIAA0288; histone deacetylase 4; OTTHUMP00000164483; histone deacetylase A |
Gene ID : | 9759 |
mRNA Refseq : | NM_006037 |
Protein Refseq : | NP_006028 |
MIM : | 605314 |
UniProt ID : | P56524 |
Chromosome Location : | 2q37 |
Function : | NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity; histone deacetylase activity (H3-K16 specific); hydrolase activity; transcription factor binding; histone deacetylase binding; protein binding; protein deacetylase activity; repressing transcription factor binding; contributes_to sequence-specific DNA binding; contributes_to transcription regulatory region DNA binding; zinc ion binding |
Products Types
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HDAC4-1045H | Recombinant Human HDAC4 Protein (T648-T1057), His tagged | +Inquiry |
HDAC4-1054H | Recombinant Human HDAC4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
HDAC4-001HCL | Recombinant Human HDAC4 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1740 | HDAC4 Fluorogenic Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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