"HDAC7" Related Products

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Recombinant Human Distone Deacetylase 7, GST-tagged

Cat. No.: HDAC7-1594H
Product Overview: Recombinant human HDAC7 (501-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: HDAC7 or Histone deacetylase 7 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. The protein encoded by HDAC7 gene has sequence homology to members of the histone deacetylase family whose protein promotes repression mediated via the transcriptional co-repressor SMRT. HDAC7 interacts with β-catenin keeping endothelial cells in a low proliferation stage.
Applications: HDAC Assay; Western Blot
Molecular Weight: 80 kDa
Expression System: Sf9 insect cells using baculovirus
Species: Human
Form: Recombinant protein stored in 50 mM Tris-HCl, PH 7.5, 150 mM NaCI, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity: >90%
Concentration: 0.1 ug/ul
Specific Activity: 80 RLU/min/ng
Sequences: 501-end
Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways: B Cell Receptor Signaling Pathway; Cell cycle; HIF-1-alpha transcription factor network; MicroRNAs in cardiomyocyte hypertrophy; Regulation of Androgen receptor activity; Signaling events mediated by HDAC Class I; Signaling events mediated by HDAC Class II; T Cell Receptor Signaling Pathway
Gene Name: HDAC7 histone deacetylase 7 [ Homo sapiens ]
Official Symbol: HDAC7
Synonyms: HDAC7; histone deacetylase 7; HD7A; HDAC7A; FLJ99588; DKFZp586J0917; histone deacetylase 7; HD7; OTTHUMP00000202813; OTTHUMP00000202814; OTTHUMP00000202823; histone deacetylase 7A
Gene ID: 51564
mRNA Refseq: NM_015401
Protein Refseq: NP_056216
MIM: 606542
UniProt ID: Q8WUI4
Chromosome Location: 12q13
Function: NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity (H3-K16 specific); hydrolase activity; transcription factor binding; histone deacetylase binding; protein binding; protein deacetylase activity; protein kinase binding; 14-3-3 protein binding; repressing transcription factor binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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