"HMOX1" Related Products

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Recombinant Human Heme Oxygenase (decycling) 1, GST-tagged

Cat. No.: HMOX1-1597H
Product Overview: Recombinant full-length human HMOX1 was expressed in E. coli cells using an N-terminal GST tag
Description: HMOX1 (Heme oxygenase 1) catalyzes the oxidative cleavage of heme to biliverdin and is one of the main genes controlling heme synthesis and catabolism. HMOX1 plays a protective role in various disorders and can ameliorate experimental MN via multiple pathways, including anti-oxidative and immunomodulatory effects.
Applications: Western Blot
Molecular Weight: 56 kDa
Expression System: E. coli
Species: Human
Form: Recombinant protein stored in 50 mM Tris-HCl, PH 7.5, 150 mM NaCI, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity: >95%
Concentration: 0.2 ug/ul
Sequences: Full-length
Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways: HIF-1-alpha transcription factor network; Iron uptake and transport; Iron uptake and transport; Keap1-Nrf2 Pathway; Mineral absorption; Mineral absorption; Oxidative Stress; Transmembrane transport of small molecules; Validated transcriptional targets of AP1 family members Fra1 and Fra2; Validated transcriptional targets of AP1 family members Fra1 and Fra2; heme degradation
Gene Name: HMOX1 heme oxygenase (decycling) 1 [ Homo sapiens ]
Official Symbol: HMOX1
Synonyms: HMOX1; heme oxygenase (decycling) 1; HO-1; HSP32; bK286B10; heme oxygenase 1; OTTHUMP00000198812; heat shock protein, 32-kD
Gene ID: 3162
mRNA Refseq: NM_002133
Protein Refseq: NP_002124
MIM: 141250
UniProt ID: P09601
Chromosome Location: 22q12
Function: enzyme binding; heme binding; heme oxygenase (decyclizing) activity; metal ion binding; oxidoreductase activity; phospholipase D activity; protein homodimerization activity; signal transducer activity

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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