Recombinant Human V-Ha-Ras Harvey Rat Sarcoma Viral Oncogene Homolog, GST-tagged

• Cat.No.: HRAS-1025H
• Product Overview: Recombinant full-length human RAS was expressed in E. coli cells using a N-terminal GST tag.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Description: The RAS gene superfamily encodes a group of closely related 21,000 dalton (p21) proteins with special affinity for guanine nucleotides (GTP). RAS and several other cellular proteins with similar biochemical properties are collectively known as G-proteins and they play key roles in a wide variety of cellular activities, including cell growth, differentiation, secretion, and protein trafficking.
• Applications: Kinase Assay; Western Blot
• Molecular Weight: 47 kDa
• Expression System: E. coli
• Form: Recombinant protein stored in 50 mM Tris-HCl, PH 7.5, 150 mM NaCI, 0.1 mM EGTA, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
• Purity: >90%
• Concentration: 0.2 ug/ul
• Sequences: Full-length
• Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Pathways: ARMS-mediated activation; Activation of NMDA receptor upon glutamate binding and postsynaptic events; Acute myeloid leukemia; Axon guidance; B cell receptor signaling pathway; BCR signaling pathway; Bladder cancer; CDC42 signaling events; Chemokine signaling pathway; Cholinergic synapse; Down-stream signal transduction; Down-stream signal transduction; EGFR1 Signaling Pathway; Endocytosis; Endocytosis

Gene Information

• Gene Name: HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog [ Homo sapiens ]
• Official Symbol: HRAS
• Synonyms: HRAS; v-Ha-ras Harvey rat sarcoma viral oncogene homolog; CTLO; HAMSV; HRAS1; K-RAS; N-RAS; RASH1; C-H-RAS; H-RASIDX; C-BAS/HAS; C-HA-RAS1; GTPase HRas; ha-Ras; p21ras; H-Ras-1; OTTHUMP00000162769; OTTHUMP00000166053; OTTHUMP00000166055; OTTHUMP00000166056; p19 H-RasIDX protein; c-has/bas p21 protein; transforming protein p21; Ha-Ras1 proto-oncoprotein; c-ras-Ki-2 activated oncogene; GTP-and GDP-binding peptide B; transformation gene: oncogene HAMSV; Ras family small GTP binding protein H-Ras
• Gene ID: 3265
• mRNA Refseq: NM_005343
• Protein Refseq: NP_005334
• MIM: 190020
• UniProt ID: P01112
• Chromosome Location: 11p15
• Function: GTPase activity; GTPase activity; Ral guanyl-nucleotide exchange factor activity; nucleotide binding; protein C-terminus binding; protein binding