Recombinant Human Heat Shock 70kDa Protein 9 (mortalin), GST-tagged

• Cat.No.: HSPA9-4852H
• Product Overview: Recombinant human Mortalin (47-end) protein was expressed in Sf9 insect cells using an N-terminal GST tag.

Specification

• Cat. No.: HSPA9-4852H
• Description: Mortalin is a mitochondrial chaperone and a member of the heat shock protein 70 family that is constitutively expressed in cells. Mortalin plays a central role in mitochondrial biogenesis through its capacity to direct the import of nuclear-encoded proteins into the mitochondria. Mortalin plays a role in the control of cell proliferation and elevated levels of mortalin have correlated with malignant transformation and poor cancer prognosis.
• Applications: Western Blot
• Molecular Weight: 97 kDa
• Expression System: Sf9 insect cells using baculovirus
• Species: Human
• Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
• Purity: >80%
• Concentration: 0.2 ug/ul
• Sequences: 47-end
• Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Pathways: RNA degradation; Tuberculosis

Gene Information

• Gene Name: HSPA9 heat shock 70kDa protein 9 (mortalin) [ Homo sapiens ]
• Official Symbol: HSPA9
• Synonyms: HSPA9; heat shock 70kDa protein 9 (mortalin); CSA; MOT; MOT2; GRP75; PBP74; GRP-75; HSPA9B; MGC4500; MTHSP75; stress-70 protein, mitochondrial; mortalin-2; p66-mortalin; OTTHUMP00000159494; mortalin, perinuclear; heat shock 70kD protein 9B; peptide-binding protein 74; 75 kDa glucose-regulated protein
• Gene ID: 3313
• mRNA Refseq: NM_004134
• Protein Refseq: NP_004125
• MIM: 600548
• UniProt ID: P38646
• Chromosome Location: 5q31
• Function: ATP binding; nucleotide binding; protein binding; unfolded protein binding