Recombinant Human Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, GST-tagged
Cat.No. : | PIP5K1A-1082H |
Product Overview : | Recombinant full-length human PIP5K1A was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PIP5K1A-1082H |
Description : | PIP5K1A or phosphatidylinositol-4-phosphate 5-kinase 1 alpha phosphorylates phosphatidylinositol-4-phosphate to form phosphatidylinositol 4, 5-bisphosphate. PIP5K1A is required for Wnt3a-induced LRP6 phosphorylation at ser1490 in mammalian cells. Wnt3a stimulates the formation of phosphatidylinositol 4,5-bisphosphates through "frizzled" and "dishevelled", the latter of which directly interacts with and activated PIP5KI. PIP5K1A-mediated PIP. |
Applications : | Kinase Assay; Western Blot |
Molecular Weight : | 86 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Species : | Human |
Form : | Recombinant protein stored in 50mM Tris-HCL, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF,0 25% glycerol. |
Specific Activity : | 1310 nmol/min/mg |
Purity : | > 90 % |
Concentration : | 0.1 ug/ul |
Sequences : | Full length |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | 3-phosphoinositide biosynthesis; Arf1 pathway; Arf6 downstream pathway; B Cell Receptor Signaling Pathway; D-myo-inositol (1,4,5)-trisphosphate biosynthesis; E-cadherin signaling in keratinocytes; Endocytosis; Fc gamma R-mediated phagocytosis; Inositol phosphate metabolism; Metabolic pathways; Osteopontin-mediated events; Phosphatidylinositol signaling system; RAC1 signaling pathway; Regulation of actin cytoskeleton; RhoA signaling pathway |
Gene Name : | PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha [ Homo sapiens ] |
Official Symbol : | PIP5K1A |
Synonyms : | PIP5K1A; phosphatidylinositol-4-phosphate 5-kinase, type I, alpha; phosphatidylinositol-4-phosphate 5-kinase type-1 alpha; PIP5KIalpha; PIP5K1-alpha; OTTHUMP00000014289; OTTHUMP00000014290; OTTHUMP00000014291; OTTHUMP00000196331; OTTHUMP00000235065; ptdIns(4)P-5-kinase 1 alpha; 68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha |
Gene ID : | 8394 |
mRNA Refseq : | NM_001135636 |
Protein Refseq : | NP_001129108 |
MIM : | 603275 |
UniProt ID : | Q99755 |
Chromosome Location : | 1q21.3 |
Function : | 1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding; kinase activity; kinase binding; nucleotide binding; protein binding; transferase activity |
Products Types
◆ Recombinant Protein | ||
PIP5K1A-6755M | Recombinant Mouse PIP5K1A Protein, His (Fc)-Avi-tagged | +Inquiry |
PIP5K1A-12828M | Recombinant Mouse PIP5K1A Protein | +Inquiry |
PIP5K1A-1727H | Recombinant Human PIP5K1A, GST-tagged | +Inquiry |
PIP5K1A-3532H | Recombinant Human PIP5K1A protein, His-tagged | +Inquiry |
PIP5K1A-3893C | Recombinant Chicken PIP5K1A | +Inquiry |
◆ Lysates | ||
PIP5K1A-3173HCL | Recombinant Human PIP5K1A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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