Recombinant Human Tec Protein Tyrosine Kinase, GST-tagged
Cat.No. : | TEC-1111H |
Product Overview : | Full-length recombinant human TEC was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | TEC-1111H |
Description : | TEC is a member of the Tec family of non-receptor protein-tyrosine kinases that are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. TEC is an integral component of T cell signaling and has a distinct role in T cell activation. Defects in TEC may be associated with myelodysplastic syndrome. TEC plays a crucial role in regulating FGF2 secretion under various physiological conditions and it inhibits CD25 expression in human T-lymphocyte. |
Applications : | Kinase Assay; Western Blot |
Molecular Weight : | 103 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Species : | Human |
Form : | Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol. |
Specific Activity : | 10 nmol/min/mg |
Purity : | > 75 % |
Concentration : | 0.1 ug/ul |
Sequences : | Full-length |
Storage : | Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | T cell receptor signaling pathway |
Gene Name : | TEC tec protein tyrosine kinase [ Homo sapiens ] |
Official Symbol : | TEC |
Synonyms : | TEC; tec protein tyrosine kinase; PSCTK4; MGC126760; MGC126762; tyrosine-protein kinase Tec; EC 2.7.10.2 |
Gene ID : | 7006 |
mRNA Refseq : | NM_003215 |
Protein Refseq : | NP_003206 |
MIM : | 600583 |
UniProt ID : | P42680 |
Chromosome Location : | 4p12 |
Function : | ATP binding; metal ion binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; transferase activity |
Products Types
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TEC-0747H | Recombinant Human TEC Protein (N2-R631), GST tagged | +Inquiry |
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◆ Lysates | ||
TEC-1153HCL | Recombinant Human TEC 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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