Recombinant Human Tousled-Like Kinase 1, GST-tagged
Cat.No. : | TLK1-1112H |
Product Overview : | Recombinant full-length human TLK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | TLK1-1112H |
Description : | TLK1 or tousled-like kinase 1 is a nuclear serine/threonine kinase that is potentially involved in the regulation of chromatin assembly. TLK1 is first described in Arabidopsis. TLK1 is a novel target of the DNA damage checkpoint that is rapidly inactivated upon exposure to ionizing radiation (IR) and the inactivation is directly mediated by the S-phase DNA damage checkpoint. The suppression of TLK1 activity after double-strand breaks in the DNA, replication blockade, or low doses of ultraviolet irradiation requires ATM, NBS and CHK1. |
Applications : | Kinase Assay; Western Blot |
Molecular Weight : | 135 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Species : | Human |
Form : | Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol. |
Specific Activity : | 6.2 nmol/min/mg |
Purity : | > 90 % |
Concentration : | 0.1 ug/ul |
Sequences : | Full-length |
Storage : | Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | TLK1 tousled-like kinase 1 [ Homo sapiens ] |
Official Symbol : | TLK1 |
Synonyms : | TLK1; tousled-like kinase 1; KIAA0137; PKU-beta; Serine/threonine-protein kinase tousled-like 1; EC=2.7.11.1; Tousled-like kinase 1; serine threonine protein kinase; SNARE protein kinase SNAK; EC 2.7.11; EC 2.7.11.1; PKU-BETA; OTTHUMP00000205035; OTTHUMP00000205036; OTTHUMP00000205037; OTTHUMP00000205038; OTTHUMP00000205039; OTTHUMP00000225037; OTTHUMP00000163076; OTTHUMP00000163077 |
Gene ID : | 9874 |
mRNA Refseq : | NM_012290 |
Protein Refseq : | NP_036422 |
MIM : | 608438 |
UniProt ID : | Q9UKI8 |
Chromosome Location : | 2q31.1 |
Function : | ATP binding; protein serine/ threonine kinase activity; nucleotide binding |
Products Types
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TLK1-1107H | Recombinant Human TLK1 Protein, MYC/DDK-tagged | +Inquiry |
TLK1-3252H | Recombinant Human TLK1, GST-tagged | +Inquiry |
TLK1-901H | Recombinant Human TLK1 protein, His&GST-tagged | +Inquiry |
◆ Lysates | ||
TLK1-589HCL | Recombinant Human TLK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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