Recombinant Human Voltage-Dependent Anion Channel-1

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Recombinant Human Voltage-Dependent Anion Channel-1

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Cat. No. : VDAC1-16H
Product Overview : Recombinant Human Voltage Dependent Anion Channel-1 produced inE. colihas a molecular mass of approximately 32 KDa.
Description : VDAC forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel allows diffusion of small hydrophilic molecules; it adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has weak anion selectivity whereas the closed state is cation-selective. rh-VDAC is expressed inE. coli.
Purity : ≥ 95% by SDS-PAGE.
Storage Buffer : Liquid. In 1% Acetic Acid.
Process : anion transport. apoptotic program. interspecies interaction between organisms
<!--<img border="0" src="productimages/CCT14 PEX-His tagged.jpg" width="250" height="221" style="border: 2px solid #3E693F" alt="VDAC1(Human), Recombinant Human Voltage-Dependent Anion Channel-1" /><a title="Protein Data Bank" style="font-family: Arial; color: black; text-decoration: none; text-underline: none; text-line-through: none" href="http://en.wikipedia.org/wiki/Protein_Data_Bank">PDB</a>rendering based on 1ck7.Available structures:<a title="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ck7" style="font-family: Arial; color: black; text-decoration: none; text-underline: none; text-line-through: none" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ck7">1ck7</a>, <a title="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1cxw" style="font-family: Arial; color: black; text-decoration: none; text-underline: none; text-line-through: none" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1cxw">1cxw</a>, <a title="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1eak" style="font-family: Arial; color: black; text-decoration: none; text-underline: none; text-line-through: none" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1eak">1eak</a>, <a title="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1gen" style="font-family: Arial; color: black; text-decoration: none; text-underline: none; text-line-through: none" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1gen">1gen</a>, <a title="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1gxd" style="font-family: Arial; color: black; text-decoration: none; text-underline: none; text-line-through: none" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1gxd">1gxd</a>, <a title="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1j7m" style="font-family: Arial; color: black; text-decoration: none; text-underline: none; text-line-through: none" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1j7m">1j7m</a>, <a title="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ks0" style="font-family: Arial; color: black; text-decoration: none; text-underline: none; text-line-through: none" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ks0">1ks0</a>, <a title="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1rtg" style="font-family: Arial; color: black; text-decoration: none; text-underline: none; text-line-through: none" href="http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1rtg">1rtg</a>--> :

Gene Name : VDAC1
Synonyms : MGC111064; PORIN; PORIN-31-HL; VDAC; VDAC-1; hVDAC1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM; Voltage-dependent anion-selective channel protein 1; voltage-dependent anion channel 1
Gene ID : 7416
mRNA Refseq : NM_003374.1
Protein Refseq : NP_003365.1
MIM : 604492
UniProt ID : P21796
Chromosome Location : 5q31
Pathway : Calcium signaling pathway
Function : protein binding.voltage-gated anion channel activity

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