"FGFR2" Related Products

Recombinant Human Fibroblast Growth Factor Receptor 2

Cat. No.: FGFR2-5002H
Product Overview: Recombinant human FGFR2 was expressed in Insect cells and purified by using conventional chromatography techniques.
Description: Fibroblast Growth Factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorigenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding. Four distinct genes encoding closely related FGF receptors, FGFR-1 to -4 are known.
Source: Human
Host: Insect cells
Form: Supplied as a lyophilized powder with no preservative. Reconstitute in sterile water to a concentration > 0.05mg/ml.
Purity: >90% pure by SDS PAGE
Molecular Mass: 170 kDa (dimer, glycosylated)
Applications: Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions
Endotoxin Levels: <0.1 ng per g of sFGF-R2 alpha
Storage: Store at -70 deg C until reconstitution. Following reconstitution product should be aliquoted and frozen at -20 deg C. Avoid repeated freeze/thaw cycles.
Gene Name: FGFR2 fibroblast growth factor receptor 2 [ Homo sapiens ]
Official Symbol: FGFR2
Synonyms: FGFR2; fibroblast growth factor receptor 2; BEK; JWS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM; FLJ98662; KSAR; FGFR-2; KSAM; OTTHUMP00000020621; OTTHUMP00000020629; BEK fibroblast growth factor receptor; CD332 antigen; FGF receptor; Jackson-Weiss syndrome; Keratinocyte growth factor receptor 2; bacteria-expressed kinase; craniofacial dysostosis 1; fibroblast growth factor receptor 2; hydroxyaryl-protein kinase; keratinocyte growth factor receptor; protein tyrosine kinase, receptor like 14; soluble FGFR4 variant 4
Gene ID: 2263
mRNA Refseq: NM_000141
Protein Refseq: NP_000132
MIM: 176943
UniProt ID: P21802
Chromosome Location: 10q26
Pathway: Endocytosis; MAPK signaling pathway; Pathways in cancer; Prostate cancer; Regulation of actin cytoskeleton; Signaling by FGFR
Function: ATP binding; fibroblast growth factor receptor activity; heparin binding; nucleotide binding; protein binding; receptor activity; transferase activity

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