"GTF2B" Related Products

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Recombinant Human General Transcription Factor II, His-tagged

Cat. No.: GTF2B-5018H
Product Overview: Recombinant GTF2B protein was expressed in E. coli and purified by using conventional chromatography techniques.
Description: GTF2B, also known as transcription factor II B, is one of several general transcription factors that make up the RNA polymerase II preinitiation complex. It localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. The protein serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. It is involved in the selection of the transcription start site.
Concentration: 0.5 mg/ml
Source: Human
Host: E.coli
Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol, 1mM DTT and 0.1 M NaCl.
Purity: > 90% by SDS - PAGE
Sequence: 1-316 amino acids: MGSSHHHHHH SSGLVPRGSH MASTSRLDAL PRVTCPNHPD AILVEDYRAG DMICPECGLV VGDRVIDVGS EWRTFSNDKA TKDPSRVGDS QNPLLSDGDL STMIGKGTGA ASFDEFGNSK YQNRRTMSSS DRAMMNAFKE ITTMADRINL PRNIVDRTNN LFKQVYEQKS LKGRANDAIA SACLYIACRQ EGVPRTFKEI CAVSRISKKE IGRCF
Molecular Mass: 27.7 kDa (248aa), confirmed by MALDI-TOF.
Storage: Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Gene Name: GTF2B general transcription factor IIB [ Homo sapiens ]
Official Symbol: GTF2B
Synonyms: GTF2B; TF2B; TFIIB; general transcription factor IIB; RNA polymerase II transcription factor IIB; S300-II
Gene ID: 2959
mRNA Refseq: NM_001514
Protein Refseq: NP_001505
MIM: 189963
UniProt ID: Q00403
Chromosome Location: 1p22-p21
Pathway: Basal transcription factors; Gene Expression; HIV Infection; Transcription
Function: DNA binding; general RNA polymerase II transcription factor activity; metal ion binding; transcription factor binding; transcription regulator activity; translation initiation factor activity; zinc ion binding

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