Active Recombinant Rat Lcn2 protein(Met1-Asn198), His-tagged
Cat.No. : | Lcn2-5176R |
Product Overview : | Recombinant Rat LCN2 (P30152) (Met 1-Asn 198) was expressed in Insect Cells, fused with a polyhistidine tag at the C-terminus. |
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Source : | Insect Cells |
Species : | Rat |
Tag : | C-His |
Protein length : | Met1-Asn198 |
Form : | Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 7.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured by its ability to bind Iron(III) dihydroxybenzoic acid [Fe(DHBA)3]. The binding of Fe(DHBA)3 results in the quenching of Trp fluorescence in Lipocalin2. It binds >1.0 μM of Fe(DHBA)3. |
Molecular Mass : | The recombinant rat LCN2 comprises 188 amino acids with and has a predicted molecular mass of 21.9 kDa. It migrates as an approximately 25 kDa band in reduced SDS-PAGE. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Lcn2 lipocalin 2 [ Rattus norvegicus ] |
Official Symbol : | Lcn2 |
Synonyms : | LCN2; lipocalin 2; neutrophil gelatinase-associated lipocalin; p25; NGAL; lipocalin-2; lipocalin 2 (oncogene 24p3); alpha-2U globulin-related protein; alpha-2-microglobulin-related protein; Sip24; |
Gene ID : | 170496 |
mRNA Refseq : | NM_130741 |
Protein Refseq : | NP_570097 |
Products Types
◆ Recombinant Protein | ||
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LCN2-001H | Recombinant Human LCN2 Protein, GST-tagged | +Inquiry |
◆ Native Protein | ||
LCN2-384H | Native Human LCN2 | +Inquiry |
◆ Lysates | ||
LCN2-2781MCL | Recombinant Mouse LCN2 cell lysate | +Inquiry |
LCN2-538RCL | Recombinant Rat LCN2 cell lysate | +Inquiry |
LCN2-2895HCL | Recombinant Human LCN2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionMutations or abnormal expression of the LCN2 protein may be associated with a variety of diseases. For example, in hereditary kidney disease, mutations in the uNGAL gene can lead to kidney damage. In addition, in inflammatory diseases, tumors, and other diseases, the expression level of LCN2 protein may also change.
Studies have shown that the expression level of LCN2 protein is associated with a variety of diseases. For example, in kidney disease, expression levels of the LCN2 protein can be elevated and can be used as one of the biomarkers to assess the extent of kidney damage. In addition, in inflammatory diseases, tumors, and other diseases, the expression level of LCN2 protein can also change.
The interaction between the LCN2 protein and other proteins or molecules is complex. For example, it can participate in lipid metabolism processes by interacting with lipid molecules. In addition, it can interact with other signal transduction molecules to participate in the signal transduction process.
Kidney function can be assessed by measuring the level of uNGAL in urine, and to help diagnose kidney disease, etc. In addition, abnormal levels of LCN2 protein expression can also be used as an indicator to assess the risk and prognosis of other diseases.
The activity of the LCN2 protein is regulated by a variety of factors. First, its expression level is regulated by gene expression. Secondly, its activity is also regulated by a variety of small molecule compounds, hormones and other substances. In addition, the LCN2 protein can also regulate its activity by interacting with other proteins.
LCN2 protein has some association with other biomarkers. For example, in kidney disease, expression levels of uNGAL can be used alongside traditional biomarkers such as creatinine to assess kidney function and degree of impairment. In addition, in diseases such as tumors, expression levels of the LCN2 protein may also change and be associated with other biomarkers.
Customer Reviews (3)
Write a reviewThey have a wide range of products and can always find LCN2 we need.
The reproducibility of LCN2 is almost 100 percent, and the results are very consistent in every experiment or application, which is an important reflection of its excellent quality.
Catalytic activity of LCN2 is really amazing, and every time it is used, it gives an unexpected catalytic effect and its performance is impressive.
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