Recombinant Human Ubiquitin Conjugating Enzyme 7


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Recombinant Human Ubiquitin Conjugating Enzyme 7

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Cat. No. : UBE2G1-09H
Product Overview : Ubiquitin Conjugating enzyme 7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 154 amino acids & having a molecular mass of 17.9 kDa.
Description : Human Ubquitin-conjugating enzyme 7 (UbcH7) is a ubiquitin-conjugating enzyme (E2) mediating c-fos degradation, transcription factor NF-B maturation, and human papilloma virus-mediated p53 and Myc protein degradation, in vitro. The ubiquitin-conjugating enzymes (E2s) are essential components of the post-translational protein ubiquitination pathway, mediating the transfer of activated ubiquitin to substrate proteins. The human UBE2L1-UBE2L4 gene could potentially encode different isoforms of the UbcH7. UBE2L3 gene, located at chromosome 22q11.2, is the only identical family member with introns and encodes a polypeptide sequence identical to that of UbcH7
Source : Escherichia Coli.
Physical Appearance : Sterile filtered colorless solution.
Purity : Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation : The protein (1 mg/ml) contains 50mM HEPES (pH-7.5) 150mM NaCl, 1mM DTT, and 10% glycerol.
Stability : Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Gene Name : UBE2G1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) [ Homo sapiens ]
Synonyms : UBE2G1; E217K; UBC7; UBE2G; ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast); UBC7; E217K; UBE2G; UBE2G1; ubiquitin-conjugating enzyme E2G 1; ubiquitin-protein ligase G1; ubiquitin carrier protein G1; ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans); ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7); EC; Ubiquitin carrier protein G1; Ubiquitin-protein ligase G1; ubiquitin-conjugating enzyme E2G; ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast).
Gene ID : 7326
mRNA Refseq : NM_003342
Protein Refseq : NP_003333
MIM : 601569
UniProt ID : P62253
Chromosome Location : 1q42; 17p13.2
Function : ligase activity; ubiquitin-protein ligase activity.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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