Recombinant Human Prolactin, His-tagged

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Recombinant Human Prolactin, His-tagged

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Cat. No. : PRL-57H
Product Overview : Recombinant Human Prolactin-His produced inE.Coliis a single, non-glycosylated polypeptide chain containing 199 amino acids fragment (29-227) and having a molecular mass of 23 kDa with an amino-terminal hexahistidine tag. The Prolactin is purified by proprietary chromatographic techniques.
Description : Prolactin is a neuroendocrine hormone synthesized primarily by the pituitary gland but also a variety of other cell types including the placenta, brain and uterus. Its primary function is to promote and maintain lactation but has also been shown to have a role in breast cancer development, regulation of reproductive function and immunoregulation.
Source : Escherichia Coli.
Physical Appearance : Sterile Filtered clear solution.
Purity : Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Formulation : Prolactin His is supplied in 1 x PBS and 50% glycerol.
Storage : Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Structure of the hormone prolactin :

Gene Name : PRL prolactin [ Homo sapiens ]
Synonyms : PRL; prolactin; OTTHUMP00000017727
Gene ID : 5617
mRNA Refseq : NM_000948
Protein Refseq : NP_000939
MIM : 176760
UniProt ID : P01236
Chromosome Location : 6p22.2-p21.3
Pathway : Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Neuroactive ligand-receptor interaction
Function : hormone activity; prolactin receptor binding

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