"PKM" Related Products

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Recombinant Human PKM, His-tagged

Cat.No.: PKM-8295H
Product Overview: Recombinant human PKM protein, fused to His-tag at N-terminus, was expressed in E.coli.
Description: Pyruvate kinase is a key enzyme in the glycolytic pathway. The M2 isoenzyme of pyruvate kinase is specifically expressed at high levels in tumour cells, and can be measured in plasma of patients with advanced breast cancer. The marker is useful for measuring disease activity, sensitivity to chemotherapy and recurrence. recombinant human M2PK is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use
Source: E. coli
Species: Human
Tag: His
Form: Liquid.
Molecular Mass: 62.4kDa
Purity: >95% by SDS-PAGE
Applications: ELISA, Western Blot, Dot Blot, Immunohistology chemistry, Immunoassays, Development of Rapid tests and other immunoassay,
Storage: ≤-20°C
Storage Buffer: Carrier free format presented in 50% glycerol buffered with saline or Tris
Gene Name: PKM pyruvate kinase, muscle [ Homo sapiens ]
Official Symbol: PKM
Synonyms: pyruvate kinase, muscle;PKM;CTHBP;OIP3;PK3;PKM2;TCB;THBP1;OIP-3;
Gene ID: 5315
MIM: 179050
UniProt ID: P14618
Chromosome Location: 15q22
Pathway: Adenine ribonucleotide biosynthesis, IMP =>ADP,ATP, organism-specific biosystem; Adenine ribonucleotide biosynthesis, IMP =>ADP,ATP, conserved biosystem; Glucose metabolism, organism-specific biosystem; Glycolysis, organism-specific biosystem; Glycolysis (Embden-Meyerhof pathway), glucose =>pyruvate, organism-specific biosystem; Glycolysis / Gluconeogenesis, conserved biosystem; Glycolysis and Gluconeogenesis, organism-specific biosystem
Function: ADP binding; ATP binding; magnesium ion binding; potassium ion binding; protein binding; pyruvate kinase activity

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