Native Human C-Reactive Protein

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Native Human C-Reactive Protein

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Cat.No. : CRP-8056H
Product Overview : Human C-Reactive Protein was purified from Human Pleural Fluid.
Description : C-Reactive Protein (CRP) is a pentameric serum protein belonging to the pentraxin family that is comprised of five identical about 23 kDa subunits. CRP is a positive acute phase reactant, the levels of which increase modestly in humans in response to inflammation, tissue injury or disease. The acute phase response develops in a wide range of acute and chronic inflammatory conditions like bacterial, viral, or fungal infections; rheumatic and other inflammatory diseases; malignancy; and tissue injury or necrosis.
Source : Human Pleural Fluid
Species : Human
Form : Liquid solution in 0.05M Tris buffer containing 0.25M NaCl
Molecular Mass : 115 kDa
Purity : >98% by SDS-PAGE
Stability : 2 years
Storage : 2-8 °C
Concentration : Typically >1.0 mg/mL
Gene Name : CRP C-reactive protein, pentraxin-related [ Homo sapiens ]
Official Symbol : CRP
Synonyms : CRP; C-reactive protein, pentraxin-related; C-reactive protein; pentraxin 1; PTX1; MGC88244; MGC149895;
Gene ID : 1401
mRNA Refseq : NM_000567
Protein Refseq : NP_000558
MIM : 123260
UniProt ID : P02741
Chromosome Location : 1q21-q23
Pathway : Classical antibody-mediated complement activation, organism-specific biosystem; Complement cascade, organism-specific biosystem; Creation of C4 and C2 activators, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem; Immune System, organism-specific biosystem; Initial triggering of complement, organism-specific biosystem; Innate Immune System, organism-specific biosystem;
Function : Gram-positive bacterial cell surface binding; binding; cholesterol binding; choline binding; low-density lipoprotein particle binding; metal ion binding; protein binding; protein homodimerization activity;

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